期刊文献+

生物制剂在结缔组织病相关间质性肺病中的应用

下载PDF
导出
摘要 结缔组织病相关间质性肺病(connective tissue disease-related interstitial lung disease,CTD-ILD)目前的治疗多采用激素联合免疫抑制剂治疗,但仍有一部分患者无法从中获益,近年来,有研究发现生物制剂在对传统疗法无效的CTD-ILD患者中取得了不错的治疗效果。本文回顾了现有的生物制剂治疗CTD-ILD的疗效及其相关不良反应,为下一步CTD-ILD的治疗选择提供依据。
作者 杨雪 唐小葵
出处 《临床肺科杂志》 2024年第4期613-618,共6页 Journal of Clinical Pulmonary Medicine
基金 重庆市科卫联合医学科研项目(No.2020MSXM033)。
  • 相关文献

参考文献3

二级参考文献22

  • 1Harris E D Jr.Rheumatoid arthritis,pathophysiology and implications for therapy[J].N Engl J Med,1990,322(18):1277-1289.
  • 2Panayi G S,Lanchbury J S,kingesley G H.The importance of the T cells in initiating and maintaining the chronic synovitis of rhermatoid arthritis[J].Arthritis Rheum,1992,35(7):729-735.
  • 3Kurosaka M,Zitff M.Immunoelectron microscopic study of the distribution of T cell subsets in rheumatoid synovium[J].J Exp Med,1983,158(4):1191-1210.
  • 4Buch M H,Vital E M,Emery P.Abatacept in the treatment of rheumatoid arthritis[J].Arthritis Res Ther,2008,10(s1):S5.
  • 5Westhovens R,Verschueren P.Translating co-stimulation blockade into clinical practice[J].Arthritis Res,Ther,2008,10(s 1):S4.
  • 6Namekawa T,Snyder M R,Yen J H,et al.Killer cell activating receptors function as constimulatory molecules on CD4+CD28 null T cells clonally expanded in rheumatoid arthritis[J].J Immunol,2000,165(2):1138-1145.
  • 7Goronzy J J,Henel G Sawai H,et al.Costimulatony pathways in rhermatoid synovitis and T-cell senescence[J].Ann N Y Acad Sci,2005,1062:189-194.
  • 8Smolen J S.Aletaha D,Koeller M,et al.New therapies for treatment of rheumatoid arthritis[J].Lancet,2007,370(9802):1861-1874.
  • 9Kremer J M,Westhovens R,Leon M,et al.Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig[J].N Engl J Med,2003,349(20):1907-1915.
  • 10Kremer J M,Dougados M,Emery P,et al.Treatment of rheumatoid arthritis with the selective costimulation modulator abatacept:twelve-month results of a phase lib double-blind,randomized,placebo-controlled trial[J].Arthritis Rheum,2005 52(8):2263-2271.

共引文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部