浙江省某医院602例肾活检结果的病理分析

Pathological analysis of 602 renal biopsy results from a hospital in Zhejiang Province

目的探究浙江省中医院肾脏疾病病理谱的分布特点。方法收集并回顾性分析2016年1月至2021年6月在浙江省中医院行肾活检的602例患者的病理资料。结果①602例患者中,男319例,女283例,男女比例为1.13∶1。年龄9~78岁,平均(44.44±15.22)岁。各病理类型的男女比例与年龄分布比较,差异有统计学意义。②原发性肾小球病(primary glomerular disease,PGD)471例,继发性肾小球病(secondary glomerular disease,SGD)117例,肾小管间质肾炎5例,遗传性肾病9例。③PGD中最常见的为免疫球蛋白A(immunoglobulin A,IgA)肾病(242例),其次为膜性肾病(110例)。④SGD中最常见的为糖尿病肾病(42例),其次为狼疮性肾炎(22例)。结论PGD是最常见的肾活检病理类型,其中以IgA肾病和膜性肾病最常见。糖尿病肾病是最常见的SGD,近年来发病率呈明显上升趋势。

Objective To exploring the distribution characteristics of renal disease pathology spectrum in Zhejiang Provincial Hospital of Traditional Chinese Medicine.Methods The pathological data of 602 patients who underwent renal biopsy at Zhejiang Provincial Hospital of Traditional Chinese Medicine from January 2016 to June 2021 were collected and retrospectively analyzed.Results①Among the 602 patients,there were 319 males and 283 females,with a male to female ratio of 1.13∶1.The patient’s age was 9-78 years old,average(44.44±15.22)years old.There are statistical differences in the gender ratio and age distribution of various pathological types.②There were 471 cases of primary glomerular disease(PGD),117 cases of secondary glomerular disease(SGD),5 cases of tubulointerstitial nephritis,and 9 cases of hereditary kidney disease.③The most common PGD is immunoglobulin(Ig)nephropathy(242 cases),followed by membranous nephropathy(110 cases).④The most common SGD was diabetes nephropathy(42 cases),followed by lupus nephritis(22 cases).Conclusion PGD is the most common pathological type of renal biopsy,with IgA nephropathy and membranous nephropathy being the most common.Diabetes nephropathy is the most common SGD.In recent years,the incidence rate of diabetes nephropathy has increased significantly.