医用钛合金表面改性及生物摩擦学性能研究进展

Progress in surface modification and biotribological properties of medical titanium alloys

Ti-6Al-4V合金是目前应用最广泛的骨植入物材料,尤其应用在人工关节、骨椎弓根螺钉等植入物领域。然而,钛合金材料表面的耐磨性不足和生物惰性是种植体失效的重要因素。为了延长钛合金种植体的使用寿命,引入表面改性来提高钛合金的性能是一种可行的解决方案。综述了钛合金材料的特性及当前存在的问题,随后对其表面生物摩擦学性能和生物活性的研究现状进行了一系列分析,并进一步综述了钛合金表面的改性手段。结果发现,通过对钛合金进行表面改性,同时提高其表面的生物摩擦学性能和生物活性,在基础科学技术上仍存在一定的挑战。因此,后续研究工作中应着重考虑钛合金表面多功能化处理设计探讨改性后的作用机理,这具有重要的理论意义和应用价值。

Ti-6Al-4V alloy is currently the most widely used bone implant material,especially in the fields of artificial joints,pedicle screws,and other implants.However,the poor wear resistance and biological inertness on the surface of titanium alloy materials are important factors for implant failure.In order to prolong the life of titanium alloy implants,surface modification treatment is a feasible method to improve the performance of titanium alloy.Firstly,the characteristics and current problems of titanium alloy materials were reviewed,and then a series of analysis on the research status of their surface biotribological properties and biological activity were conducted.Furthermore,the surface modification methods of titanium alloys were systematically reviewed.The results have showed that there are still certain challenges in basic science and technology by surface modification of titanium alloys,while improving their surface biotribological properties and biological activity.Therefore,emphasis should be placed on the design of multifunctional treatment for titanium alloy surfaces to explore the mechanism of action after modification in future research,which has important theoretical significance and application value.