CT冠状动脉造影在不同糖耐量冠心病患者诊断中的临床价值分析

Clinical Value Analysis of CT Coronary Angiography in the Diagnosis of Coronary Heart Disease Patients with Different Glucose Tolerance Levels

目的:探讨CT冠状动脉造影在不同糖耐量冠心病患者诊断中的临床价值。方法:选取本院2021年12月-2023年3月收治的冠心病患者进行研究,其中糖耐量正常的患者选取30例,作为正常组;糖耐量受损的患者选取30例,作为受损组;合并2型糖尿病的患者选取30例,作为糖尿病组。均接受CT冠状动脉造影检查,比较各组狭窄程度、病变部位、病变支数,分析糖尿量与冠状动脉狭窄程度的相关性,并对其进行2年的随访,统计主要心脏不良事件(MACE)发生情况。结果:糖尿病组冠状动脉狭窄程度重度患者显著高于正常组、受损组(P<0.05);受损组冠状动脉狭窄程度高于正常组,但对比差异不显著(P>0.05)。糖尿病组多支病变占比率高于正常组、受损组(P<0.05);受损组多支病变占比高于正常组(P<0.05)。各组冠状动脉病变部位中最少的是左主干,其余病变部位无明显差异和规律。糖耐量受损与冠状动脉狭窄程度呈正相关(P<0.05)。结论:CT冠状动脉造影在不同糖耐量冠心病患者诊断中显示出不同的狭窄程度和病变情况,通过CT冠状动脉造影能够明确糖耐量受损可促进冠心病的进展,发现糖耐量受损与冠状动脉狭窄程度密切相关,并且合并糖耐量受损的冠心病患者其发生MACE的风险也相对更高。

Objective:To explore the clinical value of CT coronary angiography in the diagnosis of coronary heart disease patients with different glucose tolerance.Methods:A study was conducted on coro⁃nary heart disease patients admitted to our hospital from December 2021 to March 2023.Among them,30 patients with normal glucose tolerance were selected as the normal group,30 patients with impaired glu⁃cose tolerance were selected as the impaired group,and 30 patients with type 2 diabetes were selected as diabetes group.All patients underwent CT coronary angiography examination to compare the degree of ste⁃nosis,lesion location,and number of lesion branches in each group.The correlation between diabetes vol⁃ume and the degree of coronary artery stenosis was analyzed,and they were followed up for 2 years to cal⁃culate the incidence of major adverse cardiac events(MACE).Results:The severity of coronary artery ste⁃nosis in diabetes group was significantly higher than that in normal group and impaired group(P<0.05);the degree of coronary artery stenosis in the damaged group was higher than that in the normal group,but the difference was not significant(P>0.05).The ratio of multi vessel disease in diabetes group was higher than that in normal group and damaged group(P<0.05);the proportion of multi vessel lesions in the dam⁃aged group was higher than that in the normal group(P<0.05).The least affected area of coronary artery disease in each group is the left main artery,while there is no significant difference or pattern in other af⁃fected areas.Impaired glucose tolerance is positively correlated with the degree of coronary artery steno⁃sis(P<0.05).Conclusion:CT coronary angiography shows different degrees of stenosis and pathological changes in the diagnosis of coronary heart disease patients with different glucose tolerance levels.Through CT coronary angiography,it can be determined that impaired glucose tolerance can promote the progression of coronary heart disease.It is found that impaired glucose tolerance is closely related to the degree of coronary artery stenosis,and patients with coronary heart disease combined with impaired glu⁃cose tolerance have a relatively higher risk of developing MACE.