孟鲁司特钠联合阿奇霉素治疗儿童肺炎支原体感染的效果

Effect of Montelukast Sodium combined with Azithromycin in the treatment of children with Mycoplasma pneumoniae infection

目的探讨孟鲁司特钠联合阿奇霉素治疗儿童肺炎支原体感染的效果。方法选取2020年3月至2022年2月菏泽市牡丹人民医院收治的96例肺炎支原体感染患儿作为研究对象,按照随机数字表分为研究组(48例)与对照组(48例)。对照组采用阿奇霉素治疗,研究组在对照组基础上联合孟鲁司特钠治疗,比较两组临床疗效、炎症因子水平及不良反应发生情况。结果研究组临床总有效率高于对照组(P<0.05)。治疗后,研究组降钙素原、C反应蛋白水平低于对照组(P<0.05)。两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论孟鲁司特钠联合阿奇霉素治疗肺炎支原体感染患儿的临床效果较好,可有效降低炎症因子水平,值得临床推广。

Objective To explore the clinical effect of Montelukast Sodium combined with Azithromycin in the treatment of children with Mycoplasma pneumoniae infection.Methods A total of 96 children with Mycoplasma pneumoniae infection admitted to Mudan People’s Hospital in Heze City from March 2020 to February 2022 were selected as the study objects.All the children were divided into the study group(48 cases)and the control group(48 cases)using the random number table method.The control group was treated with Azithromycin,while the study group was treated with Montelukast Sodium on the basis of the control group.The clinical efficacy,the levels of inflammatory factors and incidence of adverse reactions were compared between the two groups.Results The total clinical effective rate of the study group was higher than that of the control group(P<0.05).After treatment,the levels of procalcitonin and C-reactive protein in the study group were lower than those in the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion The clinical effect of Montelukast Sodium combined with Azithromycin in the treatment of children with Mycoplasma pneumoniae infection is better,which can effectively reduce inflammatory factors and is worthy of clinical promotion.