肺结核预后血清学指标研究进展

Research progress on prognostic serological indicators of pulmonary tuberculosis

我国是结核病大国,虽然肺结核的发病率较之前有所下降,但死亡率却有所上升。近年来,学者们致力于寻找一些方便、快捷并能很好评估肺结核患者病情及预后的指标。而获取血清学指标最简便易行,并能快速反应患者的病情变化情况。众多研究表明,不仅仅是传统的炎症指标,像IL-10、MIF、S100A9、sTREM-1等一些细胞因子、蛋白质分子及某些受体也对肺结核患者的病情严重程度及预后的评估有着重要价值,本文主要对这些血清学指标在肺结核的预后研究情况作了阐述,希望为临床评估肺结核患者预后提供一定的参考意义。

China is a large country with a high incidence of tuberculosis.Although the number of cases of pulmonary tuberculosis has decreased compared to before,the mortality rate has increased.Therefore,it is important to assess the condition of patients with pulmonary tuberculosis early and adjust treatment options accordingly in order to improve prognosis.In recent years,most clinical evaluations of patients with pulmo-nary tuberculosis have been based on symptoms,sputum bacteria and lung CT scans.However,these indica-tors change slowly and do not reflect changes in the patients condition in a timely manner.Therefore,our goal is to identify convenient and quick indicators that can effectively evaluate the condition of patients with pulmo-nary tuberculosis in clinical practice.This article aims to provide some valuable references for the clinical eval-uation of the prognosis of patients with pulmonary tuberculosis.