一起度假村诺如病毒感染性腹泻暴发调查与实验室检测分析

Investigation and Laboratory Analysis of an Outbreak of Norovirus Infectious Diarrhea in a Resort

目的:对发生在某度假村的感染性腹泻疫情进行调查分析,查明原因,制定防控策略,控制疫情蔓延。方法:采用现场流行病学调查和实验室检测二者结合分析,查找引起感染性腹泻的致病因子。结果:本次疫情共搜索发现确诊病例和疑似病例42例,病例临床症状主要表现为发热、呕吐、腹泻。其中发热为26人,占比61.90%;有呕吐症状为22人,占比58.38%;出现腹泻症状的人数较多,为35人,占比83.33%。对其中17例病例进行肛拭子采样,分别采用荧光PCR检测核酸和细菌学培养检测,最终在14例肛拭子标本中检测出诺如病毒GⅡ型。结论:根据病例的临床症状、流行病学调查分析和实验室检测结果判定引起此次小木屋度假村暴发感染性腹泻疫情的病原微生物为诺如病毒GⅡ型。

Objective:To investigate and analyze the infectious diarrhea epidemic in a resort,identify the causes,formulate prevention and control strategies,and control the spread of the epidemic.Method:Field epidemiological investigation and laboratory sampling were used to find the pathogenic factors causing infectious diarrhea.Result:A total of 42 confirmed and suspected cases have been identified,with the main clinical symptoms including fever,vomiting and diarrhea.Among them,26(61.90%)were febrile.22 patients(58.38%)had vomiting symptoms.The number of people with diarrhea symptoms was more,35 people,accounting for 83.33%.Field anal swabs were collected from 17 cases,nucleic acid detection byfluorescent PCR and bacteriological culture detection by bacterial culture.Finally,norovirus GⅡtype was detected in 14 cases.Conclusion:According to the clinical symptoms,epidemiological investigation and laboratory test results,the pathogenic microorganism causing the outbreak of infectious diarrhea in the chalet resort was norovirus type GⅡ.