磁控机器人胶囊内镜在药物相关性小肠黏膜损伤诊断中的应用价值

Application value of magnetic control robot capsule endoscopy in the diagnosis of drug-related small intestinal mucosal injury

目的探索磁控机器人胶囊内镜(magnetic control robot capsule endoscopy,MCRCE)在药物相关性小肠黏膜损伤中的诊断价值。方法收集2021年9月至2021年12月共119例于我院接受MCRCE检查的患者,询问患者病史及服用治疗心血管疾患药物史,根据患者服用药物状况分为未服药组和服药组,以调查问卷形式,分别统计两组患者的相关信息,采用GraphPad Prism 8.0.1软件进行t检验和χ2检验。结果两组患者年龄、肠道黏膜病变检出率及病变数量比较,差异均有显著统计学意义(P<0.0001),但性别、BMI、幽门螺杆菌感染及饮食习惯方面差异均无统计学意义(P>0.05)。结论服用抗凝药及降压药会造成肠道黏膜的损伤且更易发生多处损伤,MCRCE对肠黏膜损伤具有良好的诊断价值。

Objective To explore the diagnostic value of magnetic control robot capsule endoscopy(MCRCE)in drug-related small intestinal mucosal injury.Methods A total of 119 patients who underwent MCRCE at our hospital from Sep.2021 to Dec.2021 were enrolled in this study.Patients′medical histories and histories of cardiovascular medication intake were collected.Based on their medication status,patients were divided into non-medicated group and medicated group.Relevant information for both groups was collected through questionnaires and analyzed using t-test andχ2 test with GraphPad Prism 8.0.1 software.Results Significant statistical differences were observed between the two groups in terms of age,the detection rate of intestinal mucosal lesions,and the number of lesions(P<0.0001).However,no statistical differences were found regarding gender,BMI,H.pylori infection,and dietary habits(P>0.05).Conclusion The intake of anticoagulants and antihypertensive drugs can cause intestinal mucosal injury and is more likely to result in multiple injuries.MCRCE has demonstrated good diagnostic value for intestinal mucosal injury.