超声评估骨龄研究现状及临床应用前景

Research Status and Application Prospect of Bone Age Assessment by Ultrasonography

骨龄是了解儿童生长发育最常用且有效的指标,在多种生长发育障碍性疾病的诊断与疗效评估中发挥重要作用。临床上最常拍摄左手和腕部X线片进行骨龄评估,但其存在一定辐射风险。超声可清晰显示骨骺及次级骨化中心,进行多部位扫查、动态测量,无辐射且便捷。近年来,利用超声进行骨龄评估的相关研究及临床应用取得了较大进展。本文通过回顾最新文献,探讨肌骨超声以及定量超声在骨龄评估中的价值,并提出超声评估骨龄研究中的问题及改进方向。

Bone age,the most commonly used and effective indicator for understanding children’s growth and development,plays an important role in the diagnosis and efficacy evaluation of various growth and development disorders.Clinically,X⁃rays of the left hand and wrist are mostly taken for bone age assessment,but there is a certain radiation risk.Ultrasound can clearly display the epiphysis and secondary ossification cen⁃ter,and conveniently perform multi⁃site scanning and dynamic measurement without radiation.In recent years,great progress has been made in the research and clinical application of ultrasound in bone age assessment.This article,by reviewing the latest literature,discusses the value of musculoskeletal ultrasound and quantitative ul⁃trasound in bone age assessment,raises the problems in the study of ultrasound assessment of bone age,and suggests direction for improvement.