超声造影用于乳腺肿块良恶性鉴别诊断中的临床价值

Clinical Value of CEUS in the Differential Diagnosis of Benign and Malignant Breast Masses

目的:分析超声造影用于乳腺肿块良恶性鉴别诊断中的临床价值。方法:选取医院2021年5月~2023年8月接收的70例乳腺肿块患者作为研究对象,对其进行X射线钼靶、超声造影和手术病理检查,以术后病理检查结果作为诊断金标准,观察乳腺肿块良恶性鉴别诊断的结果,对比X射线钼靶、超声造影鉴别诊断灵敏度、特异度、准确率,并比较良恶性乳腺肿块患者的超声造影影像学特征和定量指标。结果:超声造影对乳腺肿块良恶性鉴别诊断的阳性预测值、阴性预测值、灵敏度、特异度、准确率高于X射线钼靶(P<0.05)。恶性肿块患者形态不规则者、边界模糊、穿入或扭曲血管、对比剂不均匀、充盈缺损、病灶增大等影像学特征占比率高于良性乳腺肿块患者(P<0.05)。恶性肿块患者峰值强度、曲线下面积和梯度大于良性肿块患者,达峰时间短于良性肿块患者(P<0.05);两组上升支斜率基本一致(P>0.05)。结论:超声造影可准确鉴别诊断乳腺肿块良恶性,定性和定量评估可预测乳腺肿块病变程度。

Objective:To analyze the clinical value of CEUS in the differential diagnosis of benign and malignant breast masses.Methods:70 patients with breast masses admitted to the hospital from May 2021 to August 2023 were selected as the research subjects,and they were subjected to X-ray molybdenum target,contrast-enhanced ultrasound,and surgical pathological examination.Using postoperative pathological examination results as the diagnostic gold standard,observe the results of differential diagnosis between benign and malignant breast masses,compare the sensitivity,specificity,and accuracy of X-ray molybdenum target and contrast-enhanced ultrasound differential diagnosis,and compare the ultrasound contrast imaging characteristics and quantitative indicators of patients with benign and malignant breast masses.Results:The positive predictive value,negative predictive value,sensitivity,specificity and accuracy of benign and malignant breast mass by contrast ultrasound imaging were higher than those of X-ray molybdenum target(P<0.05).The proportion of imaging features such as irregular morphology,blurred boundary,penetrating or distorting blood vessels,uneven contrast agent,filling defects,and enlarged focal lesions was higher than that of patients with benign breast masses(P<0.05).The peak intensity,area under curve and gradient were greater than those with benign masses,and the peak time was shorter than that(P<0.05);The ascending branch slope was almost consistent in both groups(P>0.05).Conclusion:CEUS can accurately identify benign and malignant breast masses,and qualitative and quantitative evaluation can predict the degree of breast mass lesions.