歌唱疗法在慢性阻塞性肺疾病患者应用效果中的Meta分析

Meta-analysis of the effect of singing therapy on patients with chronic obstructive pulmonary disease

目的系统评价歌唱疗法在慢性阻塞性肺疾病患者中的应用效果。方法计算机检索PubMed、Web of Science、Cochrane Library、CINAHL、Embase、中国知网、万方数据库、中国生物医学文献数据库、维普网中有关歌唱疗法对慢性阻塞性肺疾病患者干预效果的随机对照试验, 检索时限为建库至2023年6月30日。由2名研究者独立筛选文献、进行文献质量评价、提取数据。采用RevMan 5.4软件进行Meta分析。结果共纳入11篇文献。Meta分析结果显示, ≥10周的歌唱疗法可改善慢性阻塞性肺疾病患者的焦虑情绪(MD=-5.01, 95%CI:-5.76~-4.25, P<0.001)、抑郁情绪(MD=-4.73, 95%CI:-8.82~-0.64, P=0.020), 每次持续时间<60 min和(或)每周干预≥5次的歌唱疗法能提高慢性阻塞性肺疾病患者FEV1%预计值(MD=9.46, 95%CI:7.66~11.26, P<0.001)。结论歌唱疗法每周至少5次、每次60 min以内、持续至少10周的干预效果最佳, 但仍需更多高质量、多中心、大样本的研究进一步验证。

Objective To systematically evaluate the effect of singing therapy on patients with chronic obstructive pulmonary disease.Methods Randomized controlled trials on the effect of singing therapy in patients with chronic obstructive pulmonary disease were searched by computer from PubMed,Web of Science,Cochrane Library,CINAHL,Embase,China National Knowledge Infrastructure,Wanfang Data,China Biology Medicine disc,and VIP.The search period was from the establishment of databases to June 30,2023.Two researchers independently screened literature,performed a literature quality assessment,and extracted data.Meta-analysis was performed using RevMan 5.4 software.Results A total of 11 articles were included.Meta-analysis showed that singing therapy for 10 weeks or more could improved anxiety(MD=-5.01,95%CI:-5.76~-4.25,P<0.001),and depression(MD=-4.73,95%CI:-8.82~-0.64,P=0.020).Singing therapy with a duration of less than 60 min per session and/or five interventions per week or more could improve FEV1%predicted values(MD=9.46,95%CI:7.66~11.26,P<0.001)in patients with chronic obstructive pulmonary disease.Conclusions Singing therapy is best achieved at least five times a week,with each session lasting less than 60 minutes and lasting for at least ten weeks.However,more high-quality,multicenter and large sample studies are still needed for further validation.