角膜淋巴管新生在眼部疾病中的研究进展

Research progress of corneal lymphangiogenesis in ocular diseases

角膜淋巴管新生在眼部疾病中发挥重要作用。通常情况下,角膜是一种无血管、无淋巴管的组织,这种无血管、无淋巴管的状态对角膜的透明性和功能性至关重要。然而,一些疾病或创伤可能引起角膜血管和淋巴管的新生,从而破坏角膜的结构和功能。尽管已有多种针对角膜血管新生的药物在临床应用,但尚无特异性针对角膜淋巴管新生的药物。因此,本综述将介绍与角膜淋巴管新生相关的因素,探讨与之相关的眼部疾病,同时对目前的治疗现状进行分析,旨在为淋巴管新生相关的眼部疾病治疗提供更多的选择和可能性,为基于角膜淋巴管新生的研究和药物开发提供参考。

Corneal lymphangiogenesis plays a crucial role in ocular diseases.Normally,the cornea lacks blood vessels and lymph vessels,which are essential for maintaining transparency and function of cornea.However,certain diseases or injuries will prompt angiogenesis and lymphangiogenesis in cornea,thus disrupting the structure and function of cornea.Although various drugs targeting corneal angiogenesis have been applied in clinical practice,there is still a gap in medications targeting corneal lymphangiogenesis.Therefore,this review will introduce the factors related to corneal lymphangiogenesis,introduce related ocular diseases,and analyze the current treatment status,which will provide more options and possibilities for the treatment of lymphangiogenesis in ocular diseases and provide guidance for future research and drug development.