我院静脉配置中心抗肿瘤药不合理用药分析

Analysis of Irrational Use of Antineoplastic Drugs in Intravenous Admixture Center of our Hospital

目的分析我院静脉用药调配中心抗肿瘤药不合理用药情况,为临床抗肿瘤静脉用药提供参考,促进临床合理用药,保障肿瘤患者用药安全。方法我院2022年度住院静脉用药调配中心抗肿瘤用药医嘱10098份,依据药品说明书、相关文献等相关资料对87份不合理医嘱进行统计分析。结果我院2022年度住院静脉用药调配中心医嘱10098份,其中有不合理用药医嘱87份,每个科室均存在不合理用药情况,妇科的不合理医嘱数最多,其占比23.08%;静脉用药调配中心抗肿瘤药不合理用药情况主要包括溶媒错误(40.23%)、药物剂量不合理(29.89%)、给药顺序不合理(18.39%)、给药时间不合理(11.49%)。结论应加强我院的静脉用药调配中心抗肿瘤药不合理用药情况和抗肿瘤药溶媒管理,加强医师对抗肿瘤药物性质的认知,合理规范选择药物,同时药剂师应严格审核医嘱,以最大幅度减少不合理用药情况。

OBJECTIVE To analyze the irrational use of antineoplastic drugs in the dispensing center of intravenous drugs in our hospital,so as to provide reference for clinical antineoplastic intravenous drug use,promote clinical rational use of drugs,and ensure the safety of drug use for tumor patients.METHODS 10098 anti-tumor drug orders from intravenous drug dispensing center of our hospital in 2022 were analyzed statistically based on drug instructions and related literature.RESULTS In 2022,there were 10098 orders of intravenous drug dispensing center in our hospital,of which 87 were unreasonable,the irrational use of antineoplastic drugs in intravenous drug dispensing center mainly included solvent error(40.23%),unreasonable dosage(29.89%),unreasonable administration order(18.39%)and unreasonable administration time(11.49%).CONCLUSION It is necessary to strengthen the irrational use of antineoplastic drugs and the management of antineoplastic drug solvent in the dispensing center of intravenous drugs in our hospital,at the same time,pharmacists should strictly review the doctors advice to minimize the irrational use of drugs.