两种药物治疗飞行人员根尖周炎伴窦道的疗效观察

Efficacy of two drugs against apical periodontitis with sinus tract in flight personnel

目的研究Vitapex糊剂与氢氧化钙糊剂治疗飞行人员根尖周炎伴窦道的疗效。方法纳入2019年1月—2022年1月在海军青岛特勤疗养中心疗养的飞行人员,将经过口腔体检收治的60例患根尖周炎者作为研究对象,按随机数字表法分为对照组和观察组,各30例。对照组采用氢氧化钙糊剂进行根管诊间封药;观察组采用Vitapex糊剂进行根管诊间封药。观察2组根管预备后诊间封药的治疗效果、炎症因子水平和不良反应等。结果观察组的总有效率高达100.00%,对照组的总有效率为76.67%,观察组总有效率高于对照组,差异有统计学意义(χ^(2)=5.822,P=0.016)。治疗前2组各炎症因子水平对比差异无统计学意义(t=0.079、0.112、0.261,P=0.938、0.911、0.795);治疗后2周,观察组各炎症因子水平均低于对照组,差异有统计学意义(t=2.925、2.516、9.068,P=0.005、0.015、<0.001)。2组不良反应包括局部肿胀、感染和咬合痛。观察组不良反应发生率为10.00%,对照组不良反应发生率为3.33%,2组不良反应发生率对比差异无统计学意义(χ^(2)=0.268,P=0.605)。结论Vitapex糊剂治疗根尖周炎效果较好,能明显控制飞行人员患牙的细菌感染,使飞行人员尽快恢复工作,为航卫保障提供有利支持。

Objective To investigate the efficacy of Vitapex paste and calcium hydroxide paste against apical periodontitis with sinus tract in flight personnel.Methods Sixty pilots with periapical periodontitis admitted to our hospital between 2019 and 2022 were selected as the subjects and randomly divided into two groups with 30 cases in each.The 30 patients treated with calcium hydroxide paste served as the control group while those treated with Vitapex paste combined with minocycline and ornidazole were assigned to the observation group.The therapeutic effect,levels of factors of inflammation and adverse reactions of the two groups were observed.Results The total effective rate was 100.00%in the observation group,compared with 76.67%in the control group,so the difference was statistically significant(χ^(2)=5.822,P=0.016).There was no significant difference in VAS scores between the two groups before treatment(t=0.079,0.112,0.261,P=0.938,0.911,0.795),but the VAS score of the observation group was significantly lower than that of the control group 14 days after treatment(t=2.925,2.516,9.068,P=0.005,0.015,<0.001).Adverse reactions included stomach discomfort,infections and headache.The incidence of adverse reactions was 10.00%in the observation group and 3.33%in the control group,so there was no significant difference between the two groups(χ^(2)=0.268,P=0.605).Conclusion Vitapex paste combined with minocycline and ornidazole is effective in treating periapical periodontitis,which can help control bacterial infections of teeth of the flight personnel and quicken dental diagnosis and treatment during recuperation so that they can return to work sooner.