HIIT对超重/肥胖人群减重及血脂代谢影响的Meta分析

Efficacy of high-intensity interval training on weight loss and blood lipid metabolism with overweight or obesity: a meta-analysis

目的系统评价高强度间歇训练(HIIT)对超重/肥胖人群减重和血脂代谢的干预效果。方法计算机检索PubMed、Embase、Cochrane Library、Web of Science、CNKI和WanFang Data数据库,搜集关于HIIT与超重/肥胖人群减重、减脂和血脂代谢的随机对照试验(RCT),检索时限均从建库至2023年3月31日。由2名研究人员独立进行文献筛选和资料提取,并评价纳入研究的偏倚风险后,采用RevMan 5.4软件进行Meta分析。结果共纳入19项RCTs,包括595例超重/肥胖受试者。Meta分析结果显示:与对照组相比,HIIT干预能有效降低超重/肥胖人群体重[MD=-2.63,95%CI(-4.04,-1.23),P<0.05],BMI[MD=-1.21,95%CI(-1.95,-0.48),P<0.05],Fat%[MD=-1.66,95%CI(-2.28,-1.04),P<0.05],TG[MD=-0.13,95%CI(-0.25,-0.01),P=0.04],HDL[MD=0.14,95%CI(0.05,0.23),P<0.05]和LDL[MD=-0.26,95%CI(-0.39,-0.13),P<0.05]水平,但不能改善TC[MD=-0.15,95%CI(-0.36,0.06),P=0.15]水平。结论HIIT干预能有效改善超重/肥胖人群体重、BMI、Fat%、TG、HDL和LDL水平,尤其对超重/肥胖青少年脂蛋白水平的改善作用更加明显,但不能降低TC水平。证明HIIT可能是帮助超重/肥胖人群减重及预防心血管疾病的有效策略,具有一定推广价值。

Objective To systematically review the intervention effects of high-intensity interval training(HIIT)on weight loss and blood lipid metabolism in overweight/obese populations.Methods The computer conducted searches in the PubMed,Embase,Cochrane Library,Web of Science,CNKI,and WanFang Data database to collect randomized controlled trials(RCTs)related to HIIT and weight loss,fat reduction,and blood lipid metabolism in overweight/obese populations.The search was conducted from the inception of the databases to March 31,2023.Two researchers independently conducted literature screening and data extraction.After evaluating the risk of bias of the included studies,a meta-analysis was performed using RevMan 5.4 software.Results A total of 19 RCTs,involving 595 overweight/obese participants,were included.The meta-analysis results showed that compared wtih the control group,HIIT interventions effectively reduced body weight(MD=−2.63,95%CI−4.04 to−1.23,P<0.05),BMI(MD=−1.21,95%CI−1.95 to−0.48,P<0.05),Fat%(MD=−1.66,95%CI−2.28 to−1.04,P<0.05),TG(MD=−0.13,95%CI−0.25 to−0.01,P=0.04),HDL(MD=0.14,95%CI 0.05 to 0.23,P<0.05),and LDL(MD=−0.26,95%CI−0.39 to−0.13,P<0.05)levels but did not improve TC(MD=−0.15,95%CI−0.36 to 0.06,P=0.15)levels.Conclusion HIIT intervention can effectively improve body weight,BMI,Fat%,TG,HDL,and LDL levels in overweight/obese populations,particularly showing a more pronounced improvement in lipid profiles among overweight/obese adolescents,but it does not reduce TC levels.This study demonstrates that HIIT may be an effective strategy to assist in weight loss and prevent cardiovascular diseases in overweight/obese populations,with potential for broader application.