磁共振DWI联合MRS在诊断脑肿瘤中的临床价值研究

Clinical Value Research of Magnetic Resonance DWI Combined with MRS in Diagnosis of Brain Tumors

目的探讨在脑肿瘤诊断中,选择磁共振DWI联合MRS的价值。方法选取2020年1月—2022年10月本院收治的疑似脑肿瘤患者80例为研究对象,均实施磁共振DWI、MRS检查,以手术病理检查结果为金标准,分析磁共振DWI联合MRS检查检出情况及诊断效能,脑肿瘤与正常组织的ADC值、不同脑肿瘤的肿瘤代谢物变化。结果以手术病理检查结果为金标准,磁共振DWI联合MRS检查阳性率为88.75%,与金标准对比差异无统计学意义(P>0.05)。磁共振DWI联合MRS检查灵敏度、特异度、准确率、漏误诊率与金标准对比无统计学意义(P>0.05)。不同脑肿瘤与正常组织的ADC对比存在明显统计学意义(P<0.05),不同脑肿瘤的代谢物对比存在明显统计学意义(P<0.05)。结论在脑肿瘤诊断中选择磁共振DWI联合MRS的方案可根据ADC值与代谢物变化情况明确诊断及鉴别,从而为临床疾病的治疗提供参考。

Objective To explore value of magnetic resonance imaging(MRI)combined with magnetic resonance spectroscopy(MRS)in diagnosis of brain tumors.Methods The paper chose 80 suspected brain tumor patients admitted to our hospital from January 2020 to October 2022,treated with magnetic resonance imaging(MRI)DWI and MRS examinations,and analyzed detection and diagnostic effect of MRI DWI combined with MRS examination,ADC values of brain tumors and normal tissues,and changes of tumor metabolites of different brain tumors with gold standard of results of surgical pathological examination.Results Positive rate of magnetic resonance DWI combined with MRS examination was 88.75%based on gold standard of results of surgical pathological examination,there was no statistically significant difference compared with gold standard(P>0.05).There was no statistically significant difference in sensitivity,specificity,accuracy,and misdiagnosis rate of magnetic resonance DWI combined with MRS compared with gold standard,(P>0.05).Comparison of ADC between different brain tumors and normal tissues showed significant statistical significance(P<0.05),comparison of metabolites in different brain tumors showed significant statistical significance(P<0.05).Conclusion Combination of magnetic resonance imaging(MRI)and magnetic resonance spectroscopy(MRS)can provide clear diagnosis and differentiation based on ADC values and changes of metabolites in diagnosis of brain tumors,and provide rich reference for treatment of clinical diseases.