144例口腔颌面部间隙感染并发症及入ICU监护的危险因素分析

Risk factors for complications and ICU care of 144 cases with oral and maxillofacial space infection

目的:分析因口腔颌面部间隙感染(OMSI)住院的患者在院期间出现并发症和在重症监护室(ICU)监护的相关危险因素。方法:选择2021年1月—2022年3月就诊于徐州医科大学附属医院的OMSI患者144例。收集患者年龄、性别、住院时长、系统性疾病、体质指数(BMI)、感染来源和累及部位数目、并发症以及实验室指标,包括白细胞计数(WBC)、中性粒细胞百分比(NEU%)、C反应蛋白(CRP)等数据。采用SPSS 25.0软件包对数据进行统计学分析。结果:144例OMSI患者中,52例(36.1%)出现并发症,其中34.6%伴有气道梗阻症状;54例(37.5%)转入ICU监护。多因素Logistic回归分析显示,CRP值高(OR=1.005,95%CI:1.000~1.011,P=0.048)是患者出现并发症的危险因素。出现并发症(OR=5.249,95%CI:1.644~16.754,P=0.005)、住院时间>10 d(OR=1.166,95%CI:1.049~1.295,P=0.004)、间隙累及数目多(OR=2.719,95%CI:1.658~4.460,P<0.001)、BMI值高(OR=1.262,95%CI:1.050~1.515,P=0.013)是影响ICU监护的独立危险因素。结论:CRP、BMI值高和感染累及间隙数目多与患者出现并发症和ICU监护密切相关,需要加强对此类患者的管理,治疗过程中综合考量,避免不良预后发生。

PURPOSE:To analyze the related risk factors of complications and intensive care unit(ICU)monitoring in patients hospitalized for oral and maxillofacial space infection(OMSI).METHODS:A total of 144 patients with OMSI admitted to the Affiliated Hospital of Xuzhou Medical University from January 2021 to March 2022 were selected.The patient's age,gender,length of hospital stay,systemic diseases,body mass index(BMI),source of infection and number of involved sites,complications,and laboratory indicators including white blood cell count(WBC),neutrophil percentage(NEU%),C-reactive protein(CRP)were collected.SPSS 25.0 software package was used for data analysis.RESULTS:Among 144 patients with OMSI,52 cases(36.1%)had complications,of which 34.6%had symptoms of airway obstruction;54 cases(37.5%)were transferred to ICU.Multivariate logistic regression analysis showed that high CRP value(OR=1.005,95%CI:1.000-1.011,P=0.048)were risk factors for patients with possible complications.Complications(OR=5.249,95%CI:1.644-16.754,P=0.005),hospital stay longer than 10 days(OR=1.166,95%CI:1.049-1.295,P=0.004),more space involvement(OR=2.719,95%CI:1.658-4.460,P<0.001),and high BMI(OR=1.262,95%CI:1.050-1.515,P=0.013)were independent risk factors affecting ICU monitoring.CONCLUSIONS:High CRP and BMI values and the number of infected spaces are closely related to the complications of patients and ICU monitoring.Therefore,it is necessary to strengthen the management of such patients and take comprehensive consideration in the treatment process to avoid the occurrence of adverse prognosis.