超早期与非超早期血管内介入栓塞治疗颅内破裂动脉瘤的临床效果

Clinical Effect of Ultra-early and Non-ultra-early Intravascular Interventional Embolization in Treatment of Ruptured Intracranial Aneurysms

目的:分析超早期与非超早期血管内介入栓塞治疗颅内破裂动脉瘤的临床效果。方法:选取2020年1月-2023年1月佛山市三水区人民医院收治的颅内破裂动脉瘤患者60例为研究对象,根据入院时间分为对照组和研究组,各30例。对照组开展非超早期(发病>24h)血管内介入栓塞治疗,研究组开展超早期(发病≤24h)血管内介入栓塞治疗。比较两组住院情况、短期疗效、昏迷评分、神经功能评分、并发症发生率。结果:研究组卧床时间和住院时间短于对照组,住院费用低于对照组,差异有统计学意义(P<0.05);研究组短期治疗总有效率高于对照组,差异有统计学意义(P=0.023);治疗后,两组格拉斯哥昏迷指数(GCS)评分升高,美国国立卫生研究院卒中量表(NIHSS)评分降低,研究组GCS评分高于对照组,NIHSS评分低于对照组,差异有统计学意义(P<0.05);研究组并发症发生率低于对照组,差异有统计学意义(P=0.038)。结论:超早期血管内介入栓塞治疗颅内破裂动脉瘤效果较好,可缩短患者卧床和住院时间,降低住院费用和并发症发生率,缓解昏迷症状和神经功能损害。

Objective:To analyze the clinical effect of ultra-early and non-ultra-early intravascular interventional embolization in the treatment of ruptured intracranial aneurysms.Methods:A total of 60 patients with ruptured intracranial aneurysm were select-ed as the study objects in Foshan Sanshui District People's Hospital from January 2020 to January 2023,and were divided into control group and study group,with 30 cases in each group according to the admission time.The control group received non-ultra-early(onset>24 h)endovascular interventional embolization,and the study group received ultra-early(onset≤24 h)endovascular interventional embolization.Hospitalization,short-term efficacy,coma score,neurological function score and complication rate were compared between the two groups.Results:The bed time and hospitalization time of the study group were shorter than those of the control group,and the hospitalization cost was lower,the difference was statistically significant(P<0.05);the short-term total effective rate of the study group was higher than that of the control group,and the difference was statistically significant(P=0.023);after treatment,the Glasgow Coma Index(GCS)score increased and the National Institutes of Health Stroke Scale(NI-HSS)score decreased in both groups,the GCS score of the study group was higher than that of the control group,and the NIHSS score was lower than that of the control group,with statistical significance(P<0.05);the complication rate of the study group was lower than that of the control group,and the difference was statistically significant(P=0.038).Conclusion:The treatment of intra-cranial ruptured aneurysm with ultra-early intravascular interventional embolization is effective,which can shorten the patients'bed time and hospital time,reduce the hospitalization cost and the incidence of complications,and alleviate the symptoms of coma and nerve function damage.