Straub Rotarex系统联合药物涂层球囊治疗股浅动脉支架内狭窄闭塞性疾病的疗效

Effect of Straub Rotarex system combined with drug-coated balloon in the treatment of femoral superficial artery stent stenosis and occlusive disease

目的:探讨Straub Rotarex系统联合药物涂层球囊治疗股浅动脉支架内狭窄闭塞性疾病的临床疗效。方法:收集2021年3月至2022年8月本科收治的股浅动脉支架内再狭窄闭塞性疾病患者38例,按治疗方法不同分为对照组(n=19)和观察组(n=19)。观察组采用器械旋切联合药物涂层球囊扩张治疗,对照组采用溶栓并球囊扩张治疗,所有患者均处理单侧病变。术前、术后6个月和12个月,比较两组踝肱指数、皮肤颜色及皮温、Rutherford分级、再通率、截肢率,并进行血管闭塞评价。结果:术前两组患者临床资料比较,差异均无统计学意义(均P>0.05)。术后6个月观察组踝肱指数为0.90±0.05、再通率为(95±2)%,对照组分别为0.70±0.15、(73±3)%,观察组较对照组均明显升高(均P<0.05)。术后12个月,观察组踝肱指数为0.85±0.20、再通率为(82±3)%、截肢率为(5±1)%,对照组分别为0.60±0.03、(63±6)%、(43±5)%,组间比较差异均有统计学意义(均P<0.05)。术后6个月及12个月,观察组Rutherford分级、皮肤颜色及皮温均优于对照组(均P<0.05)。结论:Straub Rotarex系统联合药物涂层球囊治疗股浅动脉支架内再狭窄闭塞安全可靠,治疗效果优于溶栓球囊扩张治疗。

Objective:To investigate the clinical efficacy of Straub Rotarex system combined with drug-coated balloon in the treatment of femoral superficial artery stent stenosis and occlusive disease.Methods:A total of 38 patients with superficial femoral artery in-stent restenosis occlusive disease admitted to our department from March 2021 to August 2022 were collected.They were divided into the control group(n=19)and observation group(n=19)according to different treatment methods.The observation group was treated with instrument rotation combined with drug-coated balloon dilation,while the control group was treated with thrombolysis and balloon dilation.All patients were treated with unilateral lesions.The ankle-brachial index(ABI),skin color and skin temperature,Rutherford grading,reconstruction rate and amputation rate of the two groups were compared before surgery,6 months and 12 months after surgery,and vascular occlusion was evaluated.Results:There was no significant differences in the clinical data between two groups before surgery(all P>0.05).At 6 months after surgery,the ABI of the observation group was 0.90±0.05 and the reconstruction rate was(95±2)%,while those of the control group was 0.70±0.15 and(73±3)% respectively.Compared with the control group,those of the observation group were significantly increased(both P<0.05).At 12 months after surgery,the ABI of the observation group was 0.85±0.20,the reconstruction rate was(82±3)%,and the amputation rate was(5±1)%,while those of the control group was 0.60±0.03,(63±6)% and(43±5)%respectively,with the statistically differences between groups(all P<0.05).At 6 months and 12 months after surgery,the Rutherford grade,skin color and skin temperature of the observation group were better than those of the control group(all P<0.05).Conclusion:Straub Rotarex system combined with drug-coated balloon angioplasty is safe and reliable in the treatment of superficial femoral artery in-stent restenosis and occlusion,and the therapeutic effect is better than that of thrombolysis combined with balloon angioplasty.