良性发作性位置性眩晕患者手法复位后复发的影响因素分析

Analysis of factors affecting recurrence in patients with benign paroxysmal positional vertigo after manual repositioning

目的通过分析良性发作性位置性眩晕(BPPV)患者手法复位后相关影响因素,探讨可能导致BPPV复发的潜在危险因素,为降低再发率提供理论基础。方法选取2020年1月—2021年12月于扬州大学附属医院神经内科门诊确诊BPPV并治愈的170例患者。随访2年,根据是否复发分为复发组(70例)和未复发组(100例)。统计患者资料并通过logistic回归分析研究复发的危险因素。结果70例复发患者中,复发1次39例,复发2次27例,复发3次及以上的患者4例。Logistic回归分析显示女性(OR=11.623,95%CI:4.104~20.634,P<0.001)、焦虑(OR=4.200,95%CI:1.186~14.873,P=0.026)、疲劳(OR=5.025,95%CI:1.771~14.255,P=0.002)、睡眠障碍(OR=4.080,95%CI:1.152~14.447,P=0.002)、外伤(OR=4.802,95%CI:1.692~13.622,P=0.023)以及合并高血压(OR=4.938,95%CI:1.740~14.009,P<0.001)均是BPPV患者复发的危险因素,糖尿病、家族史和吸烟史与是否复发之间无明显相关性。结论性别、焦虑、疲劳、睡眠障碍、外伤以及合并高血压是BPPV患者复发的影响因素,可以更有针对性地对BPPV复发的管理和预防提供参考。

Objective This study aims to analyze the factors influencing the recurrence of benign paroxysmal positional vertigo(BPPV)following manual repositioning,revealing potential risk factors for BPPV recurrence,and providing a theoretical basis for reducing the recurrence rate.Methods A total of 170 patients diagnosed with and cured for BPPV at the Neurology Department of Affiliated Hospital of Yangzhou University between January 2020 and December 2021 were selected in this study.A 2-year follow-up was conducted,and the patients were divided into the recurrence group(n=70)and non-recurrence group(n=100)based on recurrence status.Patient data were collected and logistic regression analysis was performed to identify risk factors associated with BPPV recurrence.Results Among the 70 recurrent pa-tients,39 experienced a single recurrence,while 27 encountered two recurrences,and 4 had three or more recurrences.Logistic regression analysis showed that female(OR=11.623,95%CI:4.104-20.634,P<0.001),anxiety(OR=4.200,95%CI:1.186-14.873,P=0.026),fatigue(OR=5.025,95%CI:1.771-14.255,P=0.002),sleep disor-der(OR=4.080,95%CI:1.152-14.447,P=0.002),trauma(OR=4.802,95%CI:1.692-13.622,P=0.023)and comorbid hypertension(OR=4.938,95%CI:1.740-14.009,P<0.001)were risk factors for recurrence in BPPV patients,and diabetes,family history and smoking history were not significantly correlated with the presence or absence of recurrence.Conclusion Gender,anxiety,fatigue,sleep disorders,trauma,and hypertension were the influencing fac-tors contributing to the recurrence of BPPV.These findings offer more targeted insights for the management and preven-tion of BPPV recurrence.