疼痛干预在急性心肌梗死中的综合效应

The combined effects of pain intervention in acute myocardial infarction

急性心肌梗死作为冠状动脉疾病最严重的情况常伴有剧烈的胸痛,疼痛不仅降低了患者的治疗依从性,而且通过增加心肌耗氧、加重心脏负荷、诱发冠状动脉血管痉挛加重病情。因此,及时干预剧烈胸痛在急性心肌梗死的治疗中至关重要。现就急性心肌梗死疼痛发生机制、阿片类药物以及非甾体抗炎药在急性心肌梗死中的应用进行综述。

Acute myocardial infarction,as the most severe condition of coronary artery disease,is often accompanied by severe chest pain,which not only reduces the patient's treatment compliance,but also worsens the condition by increasing myocardial oxygen consumption,increasing cardiac load,and inducing coronary vasospasm.Therefore,timely intervention of severe chest pain is essential in the treatment of acute myocardial infarction.This article reviews the mechanism of pain in acute myocardial infarction,the use of opioids and non-steroidal anti-inflammatory drugs in acute myocardial infarction.