眼科不同级别的手术刺激对2型糖尿病患者血糖变化的影响

Effects of different levels of ophthalmic surgical stimulation on blood glucose changes in patients with type 2 diabetes mellitus

目的:探讨眼科不同级别的手术刺激对2型糖尿病患者血糖变化的影响。方法:以2021年3月至10月我院收治的236例合并2型糖尿病的眼科手术患者为研究对象,其中二级手术71例,三级手术89例,四级手术76例;再将236例患者以手术时长不同分为A、B、C 3组,A组手术时长<60 min,B组手术时长60~120 min,C组手术时长>120 min。比较不同级别手术患者术前、术后血糖值,以及A、B、C组内不同级别手术患者术前、术后血糖值。结果:二、三级手术患者术后血糖值低于本组术前,四级手术患者术后血糖值高于本组术前(P<0.05);二级、三级手术血糖波动值高于四级手术血糖波动值的绝对值(P<0.05)。A、B、C组中二、三级手术患者术后血糖值低于术前(P<0.05);A组中四级手术患者术后血糖值与术前比较差异无统计学意义(P>0.05),B组和C组中四级手术患者术后血糖值高于术前(P<0.05);A组中二、三、四级手术患者血糖波动值比较差异均无统计学意义(P>0.05),B组中二级、三级手术血糖波动值高于四级手术血糖波动值的绝对值(P<0.05),C组中三级、四级手术血糖波动值绝对值高于二级手术(P<0.05)。结论:对于伴有2型糖尿病的眼科手术患者,二级、三级手术患者术后血糖值总体呈下降趋势,而四级手术患者术后血糖值总体呈上升现象,提示临床工作者积极做好高级别手术患者的围手术期的血糖管理。

Objective:To investigate the effects of different levels of ophthalmic surgical stimulation on blood glucose in patients with type 2 diabetes mellitus(T2DM).Methods:From Mar to Oct 2021,236 patients with T2DM who underwent ophthalmic surgery in our hospital were enrolled,including 71 cases of secondary surgery,89 cases of tertiary surgery,and 76 cases of quaternary surgery.According to the operation time,the 236 patients were divided into groups A(<60 min),B(60-120 min)and C(>120 min).The preoperative and postoperative blood glucose levels were compared in patients with different levels of surgery,and in groups A,B and C.Results:The postoperative blood glucose level was lower than that before surgery in secondary and tertiary surgery,and it was higher than that before surgery in quaternary surgery(P<0.05).The fluctuation value of blood glucose in secondary and tertiary surgery was higher than that in quaternary surgery(P<0.05).In groups A,B and C,the postoperative blood glucose level was lower than that before surgery in secondary and tertiary surgery(P<0.05).In group A,there was no significant difference in the blood glucose before and after surgery in quaternary surgery(P>0.05),and in groups B and C,the postoperative blood glucose was higher than that before surgery in quaternary surgery(P<0.05).In group A,there was no difference in the fluctuation value of blood glucose at different levels of surgery(P>0.05).In group B,the fluctuation value of blood glucose in patients with secondary and tertiary surgery was higher than that in quaternary surgery(P<0.05).In group C,the fluctuation value of blood glucose in patients with tertiary and quaternary surgery was higher than that in patients with secondary surgery(P<0.05).Conclusions:For ophthalmic surgery patients with T2DM,the postoperative blood glucose values of patients undergoing secondary and tertiary surgery generally show a downward trend,while the postoperative blood glucose value of patients undergoing quaternary surgery generally shows an upward trend.It is suggested that clinical workers should actively manage the perioperative blood glucose of patients with high-level surgery.