中性粒细胞与淋巴细胞比值(NLR)、血小板与淋巴细胞比值(PLR)与老年射血分数保留心衰患者不良结局的关系

Association between Neutrophil-to-lymphocyte Ratio(NLR),Platelet-to-lymphocyte Ratio(PLR)and Adverse Outcomes in Elderly Patients with Heart Failure with Preserved Ejection Fraction

目的研究中性粒细胞与淋巴细胞比值(NLR)、血小板与淋巴细胞比值(PLR)与老年射血分数保留的心力衰竭(HFpEF)患者不良结局的关系。方法回顾性分析住院老年HFpEF患者共161例分为非不良结局组(n=100)与不良结局组(n=61),收集、比较临床资料,Logistic回归分析影响HFpEF患者不良结局的危险因素。结果与非不良结局组相比,不良结局组患者NLR、PLR值更高,差异均有统计学意义(P<0.05)。NLR、PLR是老年HFpEF患者不良结局的危险因素。结论高水平NLR、PLR与老年HFpEF患者不良结局相关,对不良结局有预测作用。

Objective To explore the association between neutrophil-to-lymphocyte ratio(NLR),platelet-to-lymphocyte ratio(PLR)and adverse outcomes in elderly patients with heart failure with preserved ejection fraction(HFpEF).Methods 161 patients with HFpEF were divided into patients with adverse outcomes group and patients without adverse outcomes group.The clinical effects of the two groups were observed.Results The NLR and PLR of patients with adverse outcomes group were higher than those of patients without adverse outcomes group,and the difference was statistically significant(P<0.05).Multivariate analysis showed that the NLR and PLR were the risk factors of adverse outcomes.Conclusion The NLR and PLR is useful for the prediction of adverse outcomes in patients with HFpEF.