硝酸甘油软膏联合九华痔疮栓治疗混合痔患者术后疼痛的疗效观察

Efficacy of Nitroglycerin Ointment Combined with Jiuhua Hemorrhoids Suppository in the Treatment of Postoperative Pain in Patients with Mixed Hemorrhoids

目的:探究硝酸甘油软膏联合九华痔疮栓对混合痔患者术后疼痛的疗效观察。方法:选取2022年5月—2022年11月入住安徽中医药大学第一附属医院肛肠二科并行混合痔外剥内扎术治疗的混合痔患者,共70例。随机分成对照组和观察组,每组35例。其中对照组患者术后予肛泰软膏换药,九华痔疮栓1粒纳肛,1次/d;观察组患者术后予硝酸甘油软膏换药,其余同对照组。比较2组患者术后疼痛程度、追加止痛药的使用率、创缘水肿以及不良反应。结果:治疗期间,观察组术后第4天和首次排便的疼痛视觉模拟评分法评分均低于对照组;观察组术后第4天追加止痛药的使用率为11.43%,显著优于对照组(37.14%);术后第4天、第7天创缘水肿评分,观察组的视觉模拟评分法评分低于对照组,差异均有统计学意义。结论:硝酸甘油软膏联合九华痔疮栓可减轻混合痔患者术后的肛门疼痛,减少创缘水肿的发生率,有利于促进创面的修复。

Objective:To observe the efficacy of nitroglycerin ointment combined with Jiuhua hemorrhoid suppository on postoperative pain in patients with mixed hemorrhoids.Methods:A total of 70 patients with mixed hemorrhoids who were admitted to the Second Anorectal Department of the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine from May 2022 to November 2022 and underwent external stripping and internal ligation of mixed hemorrhoids were selected.They were randomly divided into control group and observation group,with 35 cases in each group.The patients in the control group were given Antai ointment for dressing change after surgery,and 1 Jiuhua hemorrhoid suppository was taken into the anus once a day;the patients in the observation group were given nitroglycerin ointment for dressing change after surgery,and the rest were the same as the control group.The postoperative pain level,usage rate of additional analgesics,wound edge edema,and adverse reactions were compared between the 2 groups of patients.Results:During the treatment period,the pain VAS scores of the observation group on the fourth day after surgery and the first defecation were lower than those of the control group;the usage rate of additional analgesics in the observation group on the fourth day after surgery was 11.43%,which was significantly better than that of the control group(37.14%);the wound edge edema score on the 4th and 7th day after surgery,the VAS score of the observation group was lower than that of the control group,and the differences were statistically significant.Conclusion:Nitroglycerin ointment combined with Jiuhua hemorrhoid suppository can reduce postoperative anal pain in patients with mixed hemorrhoids,reduce the incidence of wound edge edema,and help promote wound repair.