桃红四物汤加味用于腰椎间盘突出症UBE术后的临床疗效观察

Observation on the Clinical Efficacy of Modified Taohong Siwu Decoction Combined with UBE in the Treatment of Lumbar Disc Herniation

目的:观察桃红四物汤加味用于腰椎间盘突出症单侧双通道内镜技术(Unilateral biportal endoscopic,UBE)治疗术后的临床疗效观察。方法:回顾性分析2021年6月—2022年6月符合手术指征的82例腰椎间盘突出症患者,对照组43例,采用UBE手术治疗,观察组39例,在UBE手术后口服桃红四物汤加味治疗,比较两组患者治疗后的临床疗效,治疗前后的VAS、JOA评分,C反应蛋白、D-二聚体、血红蛋白测定数值以及不良反应发生率。结果:治疗前两组患者的VAS评分及JOA评分差异无统计学意义(P>0.05),治疗后组患者两项指标均改善,且相应时间点观察组患者改善程度优于对照组(P<0.05),治疗前两组患者的C反应蛋白、D-二聚体、血红蛋白测定数值差异无统计学意义(P>0.05),术后口服中药前两组患者的三项指标数值差异无统计学意义(P>0.05),2周后两组患者的各项实验室指标较术后均改善,且观察组改善程度优于对照组(P<0.05)。两组患者治疗后的优良率及不良反应发生率差异无统计学意义(P>0.05)。结论:桃红四物汤加味用于腰椎间盘突出症UBE术后,能够明显加速术后的康复,提高治疗效果,且不会增加不良反应发生率。

Objective:To observe the clinical effect of modified Taohong Siwu decoction in the treatment of Unilateral biportal endoscopic(UBE) for lumbar disc herniation.Methods:A retrospective analysis was performed on 82 patients with lumbar disc herniation meeting surgical indications from June 2021 to June 2022,among which 43 patients in the control group were treated with UBE surgery,and 39 patients in the observation group were treated with modified Taohong Siwu decoction after UBE surgery.Clinical efficacy,VAS and JOA scores before and after treatment were compared between the two groups.CRP,D-dimer,Hb values and incidence of adverse reactions.Results:There was no significant difference in VAS score and JOA score between the two groups before treatment(P>0.05),both indexes were improved in two groups after treatment,and the improvement degree of observation group was better than control group at corresponding time points(P<0.05),there was no significant difference in CRP,D-dimer and Hb values between two groups before treatment(P>0.05),there was no statistically significant difference in the values of three indexes between the two groups before oral administration of Chinese medicine after surgery(P>0.05),after two weeks,the laboratory indexes of both groups were improved,and the improvement degree of observation group was better than that of control group(P<0.05).There was no significant difference in the excellent rate and the incidence of adverse reactions between two groups after treatment(P>0.05)Conclusion:Modified Taohong Siwu Decoction can expedite postoperative rehabilitation,enhance therapeutic efficacy,and does not elevate the incidence of adverse reactions.