1996—2022年中国市售含益生元保健食品推荐剂量

Investigation on the recommended dose of prebiotic inhealth food in China in 1996-2022

目的了解我国含益生元保健食品的推荐剂量。方法调查1996—2022年我国获批的含益生元保健食品标示信息,从总体情况、不同保健功能和不同添加方式等方面分析含益生元保健食品推荐剂量分布。结果1996—2022年我国获批有明确剂量信息的含益生元保健食品共计174个,主要涉及低聚果糖、异麦芽低聚糖、低聚木糖、聚葡萄糖与低聚半乳糖5种,以益生元复配产品居多共159个。含益生元保健食品推荐剂量范围跨度较大,总体上单一有效原料添加的含益生元保健食品剂量高于复配使用剂量。含低聚果糖保健食品推荐剂量为5.28~17500 mg/d;含异麦芽低聚糖保健食品推荐剂量为220~28000 mg/d;含低聚木糖保健食品推荐剂量为8.4~2800 mg/d;含聚葡萄糖保健食品推荐剂量为4~12120 mg/d;低聚半乳糖产品数量较少仅纳入2种,推荐剂量分别为259.8和3500 mg/d。益生元保健食品声称功能集中在通便、增强免疫力、调节肠道菌群3项,不同功能复配添加的益生元保健食品应用剂量接近总体剂量。结论我国含益生元保健食品中益生元的推荐剂量范围较大,产品中益生元以复配添加为主。

OBJECTIVE To understand the recommended dose distribution ofprebiotic-containing health food in China.METHODS The overall recommended dose ofprebiotic health food was available from the label information of approved prebiotic healthfood from 1996 to 2022;the recommended dose distribution of prebiotic-containing healthfood was analyzed from different healthy functions and different ways of addition.RESULTS There were 174 prebiotic-containing health food products with clear doseinformation,respectively,involving 5 prebiotics including Fructooligosaccharides,Galactooligosaccharides,Isomaltooligosaccharides,Xylo-oligosaccharides and Polydextrose,and the majority of prebiotics were added in combination,with 159products.The recommended dose range of prebiotic-containing health food products waswide,and in general,the dose of prebiotic-containing health food products used alone washigher than the dose used in combination.The recommended daily intake range of healthfood containing Fructooligosaccharides was 5.28-17500 mg/d,the recommended dailyintake range of health food containing Isomaltooligosaccharides was 220-28000 mg/d,thedose range of health food containing Xylo-oligosaccharides was 8.4-2800 mg/d,the doserange of health food containing Polydextrose was 4-12120 mg/d,the number of GalactoOligosaccharides products Only two kinds of products were included,with doses of 259.8mg/d and 3500 mg/d,respectively.The claimed functions of prebiotic health foodproducts were focused on laxative function,immunity enhancement,and regulation ofintestinal flora.The application dose of prebiotic health food with different functionalcompounding additions was close to the overall dose.CONCLUSION The recommendeddosage range of prebiotics in health food containing prebiotics in China is large,andprebiotics in products are mainly added by compounding.