痰培养与C反应蛋白、降钙素原联合检测对急性支气管炎的诊断价值研究

Study on the Diagnostic Value of Combined Detection of Sputum Culture,C-Reactive Protein and Procalcitonin in Acute Bronchitis

目的 探讨痰培养与C反应蛋白(CRP)、降钙素原(PCT)联合检测对急性支气管炎的诊断价值。方法 将96例急性支气管炎患者纳入观察组,同期选取我院体检的96名健康人员纳入对照组。两组均进行痰培养、 CRP、 PCT检测,比较三种检测方法单独检测与联合检测对急性支气管炎的诊断效能。结果 观察组CRP、 PCT高于对照组(P <0.05)。κ检验分析显示,联合检测与临床诊断结果具有高度一致性(κ=0.823, P <0.05)。痰培养、 CRP与PCT联合检测诊断急性支气管炎的灵敏度、特异度与准确率均高于三项指标单独检测(P <0.05)。结论 急性支气管炎患者患病期间血清炎性因子水平可出现明显升高,在检测患者CRP、 PCT水平的同时参考痰培养结果,可为该病的临床诊断提供有效数据,提高诊断准确率。

Objective To explore the diagnostic value of combined detection of sputum culture,C-reactive protein(CRP)and procalcitonin(PCT)in acute bronchitis.Methods 96 patients with acute bronchitis were selected as observation group,while 96 healthy people with physical examination in our hospital were selected as control group.Both groups received sputum culture,CRP and PCT detection.The diagnostic efficacy of single and combined detection for acute bronchitis was compared.Results The CRP and PCT of the observation group were higher than those of the control group(P<0.05).κtest analysis showed that combined detection had high consistency with clinical diagnostic results(κ=0.823,P<0.05).The sensitivity,specificity and accuracy of combined detection of sputum culture,CRP and PCT in the diagnosis of acute bronchitis were higher than those of the single detection(P<0.05).Conclusions During the onset of acute bronchitis,the levels of serum inflammatory factors can significantly increase.While detecting CRP and PCT levels in patients,combining sputum culture results can provide effective diagnostic data for the clinical diagnosis and improve diagnostic accuracy.