2型糖尿病患者并发骨质疏松的相关影响因素分析

Analysis on Related Influencing Factors of Osteoporosis in Patients with Type 2 Diabetes Mellitus

目的分析2型糖尿病(T2DM)患者并发骨质疏松(OP)的相关影响因素。方法回顾性分析2021年1月至2023年1月我院收治的89例T2DM患者的临床资料,统计其并发OP情况,并以单因素和多因素Logistic回归分析影响T2DM患者并发OP的相关因素。结果89例T2DM患者中有23例患者并发OP,OP发生率为25.84%;进一步经单因素和Logistic回归分析结果显示,年龄≥60岁、病程≥10年、BMI<24 kg/m^(2)、HbA1c≥9%、TC≥5.2 mmol/L、Ca<2.2 mmol/L是导致T2DM患者并发OP的危险因素(P<0.05)。结论T2DM患者并发OP与其年龄、病程、BMI、HbA1c、TC及Ca水平关系密切,临床上需对上述影响因素重点关注。

Objective To analyze the related influencing factors of osteoporosis(OP)in patients with type 2 diabetes mellitus(T2DM).Methods The clinical data of 89 T2DM patients admitted to our hospital from January 2021 to January 2023 were retrospectively analyzed.The OP incidence was counted,and the related factors affecting OP in T2DM patients were analyzed by univariate and multivariate Logistic regression.Results 23 cases of 89 T2DM patients had OP,with the incidence of 25.84%.Further univariate and Logistic regression analysis showed that age≥60 years,course of disease≥10 years,BMI<24 kg/m^(2),HbA1c≥9%,TC≥5.2 mmol/L,and Ca<2.2 mmol/L were risk factors for OP in T2DM patients(P<0.05).Conclusions The occurrence of OP in T2DM patients is closely related to their age,course of disease,BMI,HbA1c,TC,and Ca levels.Clinical attention should be paid to these influencing factors.