行腹腔镜辅助切除术治疗的骶尾部畸胎瘤患儿预后影响因素分析

Analysis on the Influencing Factors of Laparoscopic -Assisted Resection for Prognosis of Children with SacrococcygealTeratoma

目的 分析行腹腔镜辅助切除术治疗的骶尾部畸胎瘤患儿预后相关影响因素。方法 选取2020年6月至2022年1月在我院行腹腔镜辅助切除术治疗的60例骶尾部畸胎瘤患儿,根据患儿临床结局不同分为预后良好组和预后不良组,收集其一般资料,采用单因素和多因素Logistic回归分析影响其预后的相关因素。结果 随访6个月,60例患儿中有9例患儿预后不良,发生率为15.00%;单因素分析结果显示,行腹腔镜辅助切除术治疗的骶尾部畸胎瘤患儿预后情况不受其性别及血AFP值的影响(P<0.05),但可能受其诊断年龄、临床分型、肿瘤性状、肿瘤大小及病理类型的影响(P <0.05)。Logistic回归分析显示,诊断年龄、临床分型、肿瘤性状、病理类型是影响行腹腔镜辅助切除术治疗的骶尾部畸胎瘤患儿预后的独立因素(P <0.05)。结论 行腹腔镜辅助切除术治疗的骶尾部畸胎瘤患儿预后情况受其诊断年龄、临床分型、肿瘤性状、病理类型等因素影响,临床需对上述影响因素重点关注。

Objective To analyze the related influencing factors of laparoscopic-assisted resection for prognosis of children with sacrococcygeal teratoma.Methods 60 children with sacrococcygeal teratoma undergoing laparoscopic-assisted resection in our hospital from June 2020 to January 2022 were selected.According to the different clinical outcomes of children,they were divided into good prognosis group and poor prognosis group.The general data of were collected,and univariate and multivariate Logistic regression analysis was used to analyze the related factors affecting their prognosis.Results After 6 months of follow-up,9 of 60 children had poor prognostic outcomes,with the incidence of 15.00%.Univariate analysis results showed that the prognosis of children with sacrococcygeal teratoma undergoing laparoscopic assisted resection was not affected by their gender and blood AFP value,but might be affected by their diagnostic age,clinical classification,tumor characteristics,tumor size and pathological types(P<0.05).Logistic regression analysis showed that diagnostic age,clinical classification,tumor characteristics and pathological types were independent factors affecting the prognosis of children with sacrococcygeal teratoma undergoing laparoscopic-assisted resection(P<0.05).Conclusions The prognosis of children with sacrococcygeal teratoma undergoing laparoscopic-assisted resection is affected by factors such as diagnosis age,clinical classification,tumor characteristics,and pathological types.Clinical attention should be paid to the above influencing factors.