注意缺陷多动障碍儿童盐酸哌甲酯用药特征及趋势分析

Characteristics and trends of methylphenidate hydrochloride medication use in children with attention deficit hyperactivity disorder

目的:分析近5年来某儿童医院注意缺陷多动障碍(ADHD)患儿盐酸哌甲酯缓释片(MPH)处方特征及药物消耗趋势。方法:研究2018年至2022年ADHD患儿的MPH处方,对患儿的性别差异、年龄、单次取药量、就诊间隔及药物消耗模式进行分析。依据SPSS时间-序列模型对未来两年MPH的消耗量进行预测。结果:男女患儿的处方性别比由2018年的5.99下降为2022年的5.33;患儿平均就诊年龄约为10岁;2020年以后患儿就诊量大幅增加,2022年就诊人次是2018年的3.05倍;2022年MPH药物总DDDs是2018年的3.24倍。结论:近5年来苏州某儿童医院ADHD就诊量及MPH药物消耗量均呈上涨的趋势。

Objective:This study aims to analyze the prescription patterns and trends in the use of methylphenidate hydrochloride extended-release tablets(MPH)for children with attention deficit hyperactivity disorder(ADHD)over the past 5 years in a certain chil-dren’s hospital.Methods:MPH prescriptions for children with ADHD from 2018 to 2022 were studied and the gender differences,age distribution,single visit prescription dosage,visit intervals and drug consumption pattern of children were analyzed.Additionally,SPSS time-series modeling was utilized to predict MPH consumption for the next two years.Results:The ratio of male to female prescrip-tions decreased from 5.99 in 2018 to 5.33 in 2022;The average age of the children was approximately 10 years;There was a significant increase in the number of visits after 2020,with 2022 recording 3.05 times more visits compared to 2018.Furthermore,the total de-fined daily doses(DDDs)of MPH medications in 2022 were 3.24 times higher than in 2018.Conclusion:There is a trend of increasing the number of pediatric ADHD visits and the consumption of MPH medication are on the rise in a certain children’shospital in Suzhou.