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独活祛风活血汤配合按摩辅助西医治疗腰椎间盘突出症所致腰腿痛患者临床疗效观察

Clinical efficacy observation on Duhuo Qufeng Huoxue Decoction Combined with Massage Assisted Western Medicine in the treatment of patients with low back and leg pain caused by lumbar disc herniation
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摘要 目的:选取2020年7月至2022年11月颈肩腰腿痛医院收治腰椎间盘突出症患者131例作为研究对象.方法:根据治疗方案不同将患者分为对照组(63例,西药治疗)和观察组(68例,独活祛风活血汤配合按摩辅助西医治疗).治疗后采用《中医病症诊断疗效标准》评价两组的疗效、治疗前后采用日本骨科协会(Japanese orthopaedic association,JOA)评价腰椎功能;治疗前后采用视觉模拟评分表(Visual simulation rating sheet,VAS)评价疼痛程度;并比较两组中医症候积分;采用酶联免疫吸附法检测炎性因子[肿瘤坏死因子-α(Tumor necrosis factor-alpha,TNF-α)、白介素-1(Interleukin-1,IL-1)]水平,观察、记录治疗后两组不良反应.结果:观察组的治疗总疗效显著高于对照组(P<0.05).观察组治疗后1 w及1 m中医症候积分均显著低于对照组(P<0.05).治疗后1 w及1 m,观察组腰椎JOA评分均显著高于对照组,VAS评分均显著低于对照组(P<0.05).治疗后1 w及1 m后,观察组TNF-α、IL-1水平下降幅度均显著大于对照组(P<0.05).两组不良发应总发生率无显著差异(P>0.05).结论:独活祛风活血汤配合按摩辅助西医治疗腰椎间盘突出症所致腰腿痛患者,能提高疗效,改善腰椎功能,缓解疼痛和炎症,且安全性高. Objective:131 patients with lumbar disc herniation admitted to the Neck,Shoulder,Lumbar and Leg Pain Hospital from July 2020 to November 2022 were selected as the study subjects.Methods:According to different treatment plans,patients were divided into control group(63 cases,treated with western medicine)and observation group(68 cases,treated with Duhuo Qufeng Huoxue Decoction combined with massage and assisted with western medicine).After treatment,the curative effect of the two groups was evaluated by"Diagnostic Efficacy Standard of Traditional Chinese Medicine Diseases",and the lumbar spine function was evaluated by Japanese orthopaedic association(JOA)before and after treatment.Visual simulation rating sheet(VAS)was used to evaluate the degree of pain before and after treatment;and compare the scores of Traditional Chinese Medicine symptoms between the two groups;The inflammatory factors[tumor necrosis factor-α(TNF-α)and interleukin-1(IL-1)]were detected by enzyme-linked immunosorbent assay,and the adverse reactions of the two groups were recorded and observed after treatment.Results:The total therapeutic effect of the observation group was significantly higher than that of the control group(P<0.05).The Traditional Chinese Medicine symptom scores of the observation group 1 week and 1 month after treatment were significantly lower than those of the control group(P<0.05).1 week and 1 month after treatment,the lumbar JOA scores of the observation group were significantly higher than those of the control group,and the VAS scores of the observation group were significantly lower than those of the control group(P<0.05).1 week and 1 month after treatment,the decline in TNF-αand IL-1 levels in the observation group was significantly greater than that in the control group(P<0.05).There was no significant difference in the overall incidence of adverse reactions between the two groups(P>0.05).Conclusion:Duhuo Qufeng Huoxue Decoction combined with massage assisted with western medicine in the treatment of patients with low back and leg pain caused by lumbar disc herniation can improve the curative effect,improve lumbar function,relieve pain and inflammation,and has high safety.
作者 李丽 邵华磊 刘玉红 Li Li;Shao Hua-lei;Liu Yu-hong(Department of Pharmacy,Zhengzhou Neck,Shoulder,Waist and Leg Pain Hospital,Zhengzhou 450052,China;General Office,ZhengzhouNeck,Shoulder,Waist and Leg Pain Hospital,Zhengzhou 450052,China)
出处 《四川生理科学杂志》 2024年第3期595-597,615,共4页 Sichuan Journal of Physiological Sciences
关键词 独活祛风活血汤 按摩治疗 腰椎间盘突出症 腰腿痛 Duhuo Qufeng Huoxue Decoction massage therapy lumbar disc herniation Low back and leg pain
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