百日咳流行病学特征及防控进展

Epidemiological characteristics and prevention progress of pertussis

百日咳是一种古老的疾病,早期疫苗接种大大降低了百日咳的发病率和病死率。但近年来百日咳再现的情况在全球范围内不断被报道,进一步掌握百日咳流行病学特征,对于研发更有效的百日咳疫苗以及更好地防控和早日消除百日咳至关重要。本文主要就国内外百日咳基本流行特征、血清和分子流行病学特征以及防控进展作一综述。

Pertussis is an ancient disease,and early vaccination has greatly reduced the incidence and mortality of pertussis.However,the pertussis resurgence has been reported worldwide in recent years.Further understanding of the epidemiological characteristics of pertussis is essential for the development of more effective pertussis vaccines and for better prevention and control and early elimination of pertussis.This paper mainly reviews the basic epidemiological characteristics,seroepidemiological characteristics,molecular epidemiological characteristics and prevention and control progress of pertussis at home and abroad.