漏斗胸与脊柱侧弯的关系研究进展

Research advances on the relationship between pectus excavatum and scoliosis

漏斗胸与脊柱侧弯存在密切关系,而其诊断和治疗目前仍存在争议。一方面,漏斗胸人群中特发性脊柱侧弯的发生率明显高于普通人群,另一方面,漏斗胸患儿接受Nuss手术可能会继发获得性脊柱侧弯,也可能会减轻或加重所合并的特发性脊柱侧弯的严重程度。本文通过回顾漏斗胸合并特发性脊柱侧弯与漏斗胸术后获得性脊柱侧弯的相关临床经验、动物实验及生物力学研究结果,对其潜在病因、疾病关系及治疗方案进行总结,旨在启示外科医生以提高此类疾病的诊疗效果,为患儿带来最大获益。

Pectus excavatum(PE)is correlated closely with scoliosis while their diagnosis and treatment have remained controversial.On one hand,the incidence of idiopathic scoliosis is significantly higher in PE population than that in general population.On the other hand,PE children undergoing Nuss procedure are susceptible to acquired scoliosis and it may affect the severity of concomitant idiopathic scoliosis.This review summarized the relevant clinical experiences,animal experiments and biomechanical researches of PE combining with idiopathic scoliosis and acquired scoliosis secondary to Nuss procedure.Also,potential etiologies,disease relationship and treatment protocols were discussed.It was intended to assist surgeons in improving patient managements and outcomes.