从微型癥瘕理论探讨糖尿病血管并发症的病机转变

Study on pathogenesis of diabetic vascular complications from micro-Zhengjia

《灵枢·五变》言:“五脏皆柔弱者,善病消瘅”,心、眼、肾、皮肤、神经、血管等脆弱之脏受损,络虚瘀阻、气血壅塞不通,郁瘀痰食水积聚内结,微型癥瘕阻于目络、肢体络脉、心络、脑络发而为病,糖尿病血管并发症形成。“癥瘕致病”与糖尿病血管并发症血液流变学异常,微血管增生,血管内皮受损的病理改变有相通之处。糖尿病血管并发症的发生、发展倾向与机体先天禀赋强弱、后天条件有关。文章从“微型癥瘕致病”角度解读糖尿病微血管并发症的病机变化,有助于实践“未病先防,既病防变”的治未病理念。

Lingshu-Wubian describes that'diabetes patients with insufficient organs will suffer Xiao Dan'indicates that chronic hyperglycemia causes abnormal function of target organs such as heart,eyes,kidneys,skin,nerves,and blood vessels.Pathogenesis of micro-Zhengjia caused by deficiency of collaterals and stasis,congestion of qi and blood,accumulation of stagnant phlegm,food and water within the body is arterial block the same as abnormal blood rheology,microvascular hyperplasia,damaged vascular endothelium in diabetic vascular complication.The tendency of diabetic vascular complications to occur and develop is related to the strength of the organism's innate endowment and acquired risk factors.Learning micro-Zhengjia can help us further understand the pathogenesis and changes of diabetic vascular complications,and practice the concept of disease prevention.