老年患者血清营养素指标与骨关节炎的相关性研究

The correlation between serum nutrient biomarkers and osteoarthritis in elderly patients

目的探讨老年患者血清营养素指标与骨关节炎的相关性。方法选取2023年2—3月北京积水潭医院收治的607例老年患者为研究对象,根据是否诊断为骨关节炎分为骨关节炎组与非骨关节炎组,收集2组患者一般资料及总蛋白、白蛋白、球蛋白、钙、磷、钾等血清营养素指标。采用logistic回归分析血清营养素指标与骨关节炎的相关性。结果骨关节炎组患者血清总蛋白、白蛋白、球蛋白、磷、钠、氯水平高于非骨关节炎组患者(P<0.05);logistic回归分析显示,血清钾(OR=0.635,95%CI:0.420~0.960)、血清钙(OR=0.025,95%CI:0.005~0.124)与骨关节炎的发生具有相关性。结论老年患者血清钾、血清钙与骨关节炎的发生呈负相关关系。

Objective To explore the correlation between serum nutrient biomarkers and osteoarthritis in elderly patients.Methods A total of 607 elderly patients admitted to Beijing Jishuitan Hospital from February to March 2023 were selected.The patients were divided into osteoarthritis group and non-osteoarthritis group according to whether they had osteoarthritis or not.General data and serum nutrient biomarkers of total protein,albumin,globulin,calcium,phosphorus and potassium were collected.The correlation between serum nutrient biomarkers and osteoarthritis was analyzed by logistic regression analysis.Results The level of serum total protein,albumin,globulin,phosphorus,sodium and chlorine were significantly higher than those in non-osteoarthritis group(P<0.05).Logistic regression analysis showed that serum potassium(OR=0.635,95%CI:0.420-0.960)and serum calcium(OR=0.025,95%CI:0.005-0.124)were correlated with the osteoarthritis.Conclusions Serum potassium and calcium are negatively correlated with the osteoarthritis.