乳腺癌患者血脂管理的证据总结

Evidence summary for lipid management in patients with breast cancer

目的:检索、评价并汇总乳腺癌患者血脂管理的证据,为乳腺癌患者的血脂管理提供循证依据。方法:系统检索并筛选各指南网站、专业学会网站及综合数据库中与乳腺癌患者血脂管理相关的文献,检索时限为建库至2023年6月12日。由4名研究者独立完成文献的质量评价及证据提取,汇总并整合证据。结果:共纳入11篇文献,包括2篇指南、4篇专家共识、5篇系统评价,围绕确定调脂目标、调节生活方式、药物降脂管理和定期监测随访4个主题,汇总形成了24条证据。结论:本证据总结对促进乳腺癌患者血脂管理、降低乳腺癌患者心血管风险具有指导意义,为改善乳腺癌患者的疾病预后提供了新的思路。

Objective:To retrieve,evaluate and summarize the evidence on lipid management in breast cancer patients,so as to inform evidence-based practice.Methods:Literatures related to lipid management in breast cancer patients were systematically retrieved and screened from guideline websites,professional association websites and comprehensive databases.The retrieval period was from the inception of databases to June 12,2023.The quality evaluation and evidence extraction of literature were independently completed by 4 researchers,and the evidence was systematically summarized and integrated.Results:A total of 11 articles were included,including two guidelines,four expert consensus,and five systematic reviews.Finally,a total of 24 pieces of evidence were summarized from four aspects on determining lipid adjustment goals,regulating lifestyles,drug lipid-lowering management,and regular follow-up.Conclusion:This article provides evidences for improving lipid management and decreasing cardiovascular disease risk,and provides a new way to improve the prognosis of breast cancer patients.