临床药师干预对Ⅰ类切口围术期预防用抗生素使用情况的影响分析

Analysis of the effect of clinical pharmacist intervention on the use of prophylactic antibiotics in perioperative period of type I incision

目的:分析临床药师干预对Ⅰ类切口围术期预防用抗生素使用情况的影响。方法:利用霍邱县第二人民医院医院信息系统(HIS)检索2020年1月—2021年12月行Ⅰ类切口手术治疗的2570例住院患者为研究对象,以临床药师对围术期预防用抗生素使用情况进行干预的时间节点(2021年1月1日)为界限将其分为对照组(1212例)与干预组(1358例),比较两组患者预防用抗生素使用率及合理率。结果:对照组预防性抗生素使用率为60.81%,高于干预组的预防性抗生素使用率29.38%,差异有统计学意义(P<0.05);对照组围术期预防性抗生素使用合理率为60.89%,低于干预组的围术期预防性抗生素使用合理率98.74%,差异有统计学意义(P<0.05)。结论:临床药师通过专项点评、医嘱审核、抗生素培训等措施能显著降低Ⅰ类切口围术期预防用抗生素使用率,并提高其使用合理率。

Objective To analyze the effect of clinical pharmacist intervention on the use of prophylactic antibiotics in perioperative period of type I incision.Methods The hospital information system(HIS)of the Second People's Hospital of Huoqiu County was used to retrieve 2570 inpatients who underwent type I incision surgery from January 2020 to December 2021 as the research object.The time node(January 1,2021)for clinical pharmacists to intervene in the use of prophylactic antibiotics during perioperative period was divided into control group(1212 cases)and intervention group(1358 cases).The utilization rate and reasonable rate of prophylactic antibiotics were compared between the two groups.Results The use rate of prophylactic antibiotics in the control group was 60.81%,which was higher than that in the intervention group(29.38%),and the difference was statistically significant(P<0.05).The reasonable rate of perioperative prophylactic antibiotic use in the control group was 60.89%,which was lower than that in the intervention group(98.74%),and the difference was statistically significant(P<0.05).Conclusions Through special comments,doctor's advice review,antibiotic training and other measures,clinical pharmacists can significantly reduce the use rate of perioperative prophylactic antibiotics in type I incision and improve the rational use rate.