基于文献可视化分析中医药治疗HPV感染的研究热点及趋势

Research Hotspots and Trends of Traditional Chinese Medicine in the Treatment of HPV Infection Based on Literature Visualization

目的通过对中医药治疗HPV感染这一主题进行文献可视化分析,把握该领域的研究现况、热点及发展趋势,发现目前亟待解决的问题并提出具体建议。方法筛选中国知网(CNKI)资料库与中医药治疗HPV感染相关文献,运用可视化分析软件CiteSpace进行作者及关键词分析。结果共纳入文献1128篇,发文量总体呈上升趋势,其中2006年、2018年为开始突破性增长的年份;作者可视化分析显示,吴冬梅、任青玲为发文量最多的作者,刘倩、薛晓鸥、朱丽红为发文量排名第2的作者;关键词共现分析显示,中介中心性大于0.1的关键词共20个,其中与疾病进展相关关键词有3个、与中医辨证论治相关2个、与治疗方法相关8个、与疾病机制相关1个、与后遗症评估相关4个、与研究类型相关2个;关键词聚类分析显示,主要类团包括#0宫颈癌、#1综述、#2带下病、#3艾灸、#4宫颈肿瘤、#5尿潴留、#6疗效、#7化疗、#8数据挖掘、#9中医证型;关键词突现分析显示,与中医药治疗HPV感染相关关键词爆发年份为2015-2023年。结论中医药治疗HPV感染研究热点主要为HPV感染的体质学说讨论、临床中药运用及宫颈癌术后后遗症治疗,后续发展动力将与加强团队间合作及完善研究类型及数据资料相关。

Objective To carry out literature visualization analysis on the theme of traditional Chinese medicine in the treatment of HPV infection,grasp the research status,hot spots and development trends in this field,find out the urgent problems to be solved and put forward specific suggestions.Methods Literature related to the treatment of HPV infection in CNKI database was screened.And visualization analysis software CiteSpace was used to analyze authors and keywords.Results A total of 1128 articles that met the requirements were included.The number of publications shows an overall upward trend,with 2006 and 2018 as the years when breakthrough growth began.The visual analysis of authors shows that WU Dong-mei and REN Qing-ling were the authors with the largest number of publications,while LIU Qian,XUE Xiao-ou and ZHU Lihong were the authors with the second largest number of publications.Keyword co-occurrence analysis showed that a total of 20 keywords with intermediate centrality greater than 0.1 were related to disease progression,among which 3 keywords were related to TCM syndrome differentiation and treatment,2 keywords were related to treatment methods,8 keywords were related to disease mechanism,1 keyword was related to sequelae evaluation,4 keywords were related to study type,and 2 keywords were related to study type.Keyword cluster analysis showed that the main clusters included#0 cervical cancer,#1 review,#2 leucorrhea,#3 moxibustion,#4 cervical cancer,#5 urinary retention,#6 efficacy,#7 chemotherapy,#8 data mining,#9 TCM syndrome type.Keyword burst analysis showed that the outbreak years of keywords related to TCM treatment of HPV infection were 2015-2023.Conclusion The research hotspots of traditional Chinese medicine in the treatment of HPV infection are mainly the discussion of constitution theory of HPV infection,the application of clinical traditional Chinese medicine and the treatment of sequelae after cervical cancer surgery.The follow-up development momentum will be related to strengthening team cooperation and improving research types and data.