红外热像技术辅助下探讨中药薰药治疗风寒湿痹型膝骨关节炎的临床研究

A clinical study on treating wind-cold-dampness arthritis of knee osteoarthritis by TCM medicine fumigation with the assistance of infrared thermal imaging technology

目的:观察中药熏药治疗风寒湿痹型膝骨关节炎(Knee Osteoarthritis,KOA)患者的临床疗效,并采用医用红外热成像仪进行疗效系统评价。方法:根据随机数字表法将60例风寒湿痹型KOA患者分为治疗组与对照组,对照组予口服艾瑞昔布片,治疗组在对照组治疗的基础上配合柳州市中医医院中药验方进行膝部中药熏药治疗。治疗8周后,比较两组治疗前后膝周疼痛视觉模拟评分法(Visual Analogue Scale,VAS)评分、西安大略和麦克马斯特大学骨关节炎指数量表(Western Ontario and McMaster Universities Osteoarthritis Index,WOMAC)评分、超敏C反应蛋白、红细胞沉降率、经络穴位皮温等的变化情况。结果:治疗组与对照组VAS评分和WOMAC评分及炎症因子水平较治疗前均显著降低(P<0.01),治疗组VAS评分和WOMAC评分及炎症因子水平均低于对照组(P<0.01);两组治疗后主要穴位均温显著高于治疗前(P<0.01),且治疗组较对照组的均温改善显著(P<0.01);治疗组愈显率显著高于对照组,两组患者的愈显率进行比较,P<0.05。结论:中药验方熏药治疗方案能改善风寒湿痹型KOA患者的证候和有效缓解疼痛,显著降低KOA评分和提高相应经络穴位的红外皮温,并通过红外热像技术得到证实,可为临床适宜技术推广与应用提供可靠的临床数据和值得借鉴的研究思路。

Objective:To observe the clinical efficacy of TCM medicine fumigant in the treatment of patients with wind-cold-dampness arthritis of KOA,and to conduct a systematic evaluation of the efficacy by medical infrared thermal imaging device.Methods:According to the random number table method,60 cases of KOA of wind-cold-dampness type were divided into the treatment group and the control group.The control group was treated with Irecoxib tablets.The treatment group was givenO TCM prescriptions more.After 8 weeks of systemic treatment,Changes in the visual analogue scale(VAS)score of knee pain,Western Ontario and McMaster University Osteoarthritis Index(WOMAC)score,high-sensitivity C-reactive protein,erythrocyte sedimentation rate,and skin temperature of meridian points were observed.Results:The VAS score,WOMAC score and inflammatory factor levels in the treatment group and the control group were significantly lower than before treatment(P<0.01),and the VAS score,WOMAC score and inflammatory factor levels in the treatment group were lower than the control group(P<0.01).The average temperature of main acupoints after treatment in the two groups was significantly higher than before treatment(P<0.01),and the average temperature in the treatment group was significantly improved compared with the control group(P<0.01).The cure rate in the treatment group was significantly higher than the control group.The recovery rate in the two groups showed a different(P<0.05).Conclusion:The treatment program of TCM fumigation can improve the symptoms of patients with KOA of wind-cold-dampness type to a certain extent and effectively relieve the pain,and significantly reduce the KOA scorees and improve the infrared skin temperature of the corresponding meridian points.This topic experiments can provide reliable clinical data and research ideas for the promotion and application of clinically appropriate technologies.