不同时机内镜治疗急性上消化道出血的效果及对止血时间、再次出血率和SF-36评分的影响

Effects of endoscopic treatment of acute upper gastrointestinal bleeding at different times and its influences on hemostasis time,rebleeding rate and SF-36 score

目的探析不同时机内镜治疗急性上消化道出血(AUGIB)的效果及对止血时间、再次出血率和健康调查简表(SF-36)评分的影响。方法选择2020年1月至2021年10月收治的100例AUGIB患者作为研究对象,按入院时间不同将其分为A组(25例,入院接受内镜治疗≤6 h)、B组(25例,入院接受内镜治疗>6~12 h)、C组(25例,入院接受内镜治疗>12~24 h)和D组(25例,入院接受内镜治疗>24~48 h)。比较四组患者的止血时间、再次出血率及SF-36评分。结果A组的止血时间最短;四组的止血时间比较,差异具有统计学意义(P<0.05)。B组的再次出血率最高,C组、D组次之;四组的再次出血率比较,差异具有统计学意义(P<0.05)。治疗后,四组的SF-36评分均升高,且A组高于B组、C组和D组,差异具有统计学意义(P<0.05)。结论AUGIB患者于发病后6 h内及时入院接受内镜治疗,可以缩短止血时间,降低再次出血率,提高SF-36评分,减轻上消化道受损情况,值得推荐。

Objective To explore the effects of endoscopic treatment of acute upper gastrointestinal bleeding(AUGIB)at different times and its influences on hemostasis time,rebleeding rate and the MOS Item Short From Health Survey(SF-36)score.Methods A total of 100 patients with AUGIB admitted from January 2020 to October 2021 were selected as the research objects.According to the different admission time,the patients were divided into group A(25 cases,admission endoscopic treatment≤6 h),group B(25 cases,admission endoscopic treatment>6-12 h),group C(25 cases,admission endoscopic treatment>12-24 h)and group D(25 cases,admission endoscopic treatment>24-48 h).The hemostasis time,rebleeding rate and SF-36 score of the four groups were compared.Results The hemostasis time of the group A was the shortest;there was statistically significant difference in the hemostatic time of the four groups(P<0.05).The rebleeding rate of the group B was the highest,followed by the group C and the group D;there was statistically significant difference in the rebleeding rate of the four groups(P<0.05).After treatment,the SF-36 score of the four groups increased,and that in the group A was higher than the group B,the group C and the group D,and the difference was statistically significant(P<0.05).Conclusion The timely admission of patients with AUGIB to endoscopic treatment within 6 h after the onset of the disease can shorten the hemostasis time,reduce the rebleeding rate,improve the SF-36 score,and reduce the damage of the upper digestive tract,which is worthy of recommendation.