强直性脊柱炎的综合治疗进展

Progress in comprehensive treatment of ankylosing spondylitis

强直性脊柱炎是临床中一种发病率较高的自身免疫性疾病,其特征是脊柱和骶髂关节异常骨化和强直,随着疾病的进一步发展,最终导致患者生活质量急剧下降。目前可以选择的治疗方法较多,早期干预和综合治疗是关键,包括药物治疗、康复训练、手术治疗等,虽然可以选择的治疗方法较多,但因为其发病机制尚不完全清楚,在临床治疗中仍是一个难点,本文系统梳理近些年强直性脊柱炎治疗的文献,为进一步优化综合治疗策略提供参考。

Ankylosing spondylitis is an autoimmune disease with a high incidence rate in clinic.It is characterized by abnormal ossification and ankylosis of the spine and sacroiliac joints.With the further development of the disease,the quality of life of patients will eventually decline sharply.At present,there are many treatment methods that can be chosen,and early intervention and comprehensive treatment are key,including drug therapy,rehabilitation training,surgical treatment,etc.Although there are many treatment methods to choose from,its pathogenesis is not fully understood,and it is still a difficult point in clinical treatment.This article systematically reviews the literature on the treatment of ankylosing spondylitis in recent years,providing reference for further optimizing comprehensive treatment strategies.