睡眠剥夺对机体及谵妄的影响研究进展

Research progress on the effects of sleep deprivation on organism and delirium

睡眠是每个人必需的生理过程。人的一生约1/3的时间与睡眠相伴,睡眠剥夺(SD)或睡眠障碍影响机体从胚胎至老年的各个阶段。手术以及全身麻醉后常常发生术后谵妄,尽管常见,但谵妄发生的确切机制目前在世界范围内尚未阐明,亟待研究。近年来许多研究以及实践表明,SD与谵妄的发生存在联系,本综述总结了近期关于SD对机体的影响以及SD与谵妄相互作用的部分文章,为临床进一步研究SD对机体的损害及SD与谵妄之间的关系提供参考。

Sleep is an essential physiological process for everyone.About one third of a person's life is spent sleeping,and sleep deprivation(SD)or sleep disorders affect all stages of the body from embryo to old age.Postoperative delirium often occurs after surgery and general anesthesia.Although common,the exact mechanism of delirium has not been clarified in the world and needs to be studied urgently.In recent years,many studies and practices have shown that SD is related to the occurrence of delirium.This review summarizes some recent articles on the influence of SD on the body and the interaction between SD and delirium,so as to provide references for further clinical research on the damage of SD on the body and the relationship between SD and delirium.