硫酸镁联合拉贝洛尔治疗妊娠期高血压疾病效果分析

Effect analysis of magnesium sulfate combined with labetalol in the treatment of hypertensive diseases during pregnancy

目的探讨妊娠期高血压疾病采用硫酸镁联合拉贝洛尔治疗的效果。方法选择60例妊娠期高血压疾病患者为研究对象,采用随机数字表法分为对照组和研究组,每组30例。对照组给予硫酸镁治疗,研究组在对照组基础上采用拉贝洛尔治疗,比较两组舒张压(DBP)、收缩压(SBP)、平均动脉压(MAP)及不良妊娠结局。结果治疗前,两组DBP、SBP、MAP水平比较差异均无统计学意义(P>0.05);治疗后,两组DBP、SBP、MAP水平均优于治疗前,且研究组优于对照组(P<0.05);研究组不良妊娠结局发生率低于对照组(P<0.05)。结论妊娠期高血压疾病采用硫酸镁联合拉贝洛尔治疗效果较好,可改善患者血压水平,降低患者不良妊娠结局发生风险,保护母婴健康,值得临床推广与应用。

Objective To investigate the effect of magnesium sulfate combined with labetalol in the treatment of hypertensive diseases during pregnancy.Methods A total of 60 patients with hypertensive diseases in pregnancy were selected as the study objects,and were divided into control group and study group by random number table method,with 30 cases in each group.The control group was treated with magnesium sulfate,and the study group was treated with labetalol on the basis of the control group.Diastolic blood pressure(DBP),systolic blood pressure(SBP),mean arterial pressure(MAP)and adverse pregnancy outcomes were compared between the two groups.Results Before treatment,there were no significant differences in DBP,SBP and MAP levels between the two groups(P>0.05).After treatment,the levels of DBP,SBP and MAP in both groups were better than before treatment,and the study group was better than the control group(P<0.05).The incidence of adverse pregnancy outcome in study group was lower than that in control group(P<0.05).Conclusion Magnesium sulfate combined with labetalol can improve blood pressure,reduce the risk of adverse pregnancy outcomes,and better protect maternal and infant health,which is worthy of clinical promotion and application.