双水平气道正压通气联合纤支镜肺泡灌洗治疗重症肺炎伴呼吸衰竭的疗效分析

Efficacy Analysis of Bi-level Positive Airway Pressure Ventilation Com⁃bined with Fibrinoscopic Alveolar Lavage in the Treatment of Severe Pneu⁃monia with Respiratory Failure

目的探究双水平气道正压通气联合纤支镜肺泡灌洗治疗对重症肺炎伴呼吸衰竭患者的治疗效果。方法选取2019年1月—2023年6月于泰州市姜堰中医院治疗的60例重症肺炎伴呼吸衰竭患者的临床资料进行回顾性分析,按其治疗方案不同分为两组。对照组(30例)实行纤支镜肺泡灌洗+常规通气治疗,观察组(30例)实行双水平气道正压通气+纤支镜肺泡灌洗治疗。比较两组治疗前后的炎性指标及并发症情况。结果观察组与对照组治疗后的炎性指标低于治疗前,差异有统计学意义(P<0.05);观察组的并发症总发生率为6.67%,低于对照组的33.33%,差异有统计学意义(χ^(2)=6.667,P=0.010)。结论双水平气道正压通气与纤支镜肺泡灌洗治疗法可以有效改善重症肺炎伴呼吸衰竭患者的炎症程度,降低并发症发生率。

Objective To investigate the therapeutic effect of bi-level positive airway pressure ventilation combined with fibrinoscopic alveolar lavage treatment on patients with severe pneumonia with respiratory failure.Methods The clinical data of 60 patients with severe pneumonia with respiratory failure treated in Taizhou Jiangyan Hospital of Tra⁃ditional Chinese Medicine between January 2019 and June 2023 were retrospectively analyzed,and were divided into two groups according to the differenct treatment plan.The control group(30 cases)was treated with fibrinoscopic al⁃veolar lavage+conventional ventilation,and the observation group(30 cases)was treated with bi-level positive airway pressure ventilation+fibrinoscopic alveolar lavage.Inflammatory indexes before and after treatment and complica⁃tions were compared between two groups.Results The inflammatory indexes of the observation group and the control group after treatment were lower than those before treatment,and the difference was statistically significant(P<0.05).The incidence of complication in the observation group was 6.67%,33.33%lower than in the control group,and the difference was statistically significant.(χ^(2)=6.667,P=0.010).Conclusion Bi-level positive airway pressure ventilation and fibrinoscopic alveolar lavage treatment method can effectively improve the degree of inflammation and reduce the incidence of complications in patients with severe pneumonia with respiratory failure.