非侵袭性真菌性鼻-鼻窦炎扩大的鼻内镜鼻窦手术治疗分析

Analysis of Endoscopic Sinus Surgery for Noninvasive Fungal Rhinosinusitis

目的分析鼻内镜鼻窦手术应用于非侵袭性真菌性鼻-鼻窦炎扩大患者中的使用价值。方法选取2022年6月—2023年6月临沂河东医院收治的72例非侵袭性真菌性鼻-鼻窦炎扩大患者为研究对象,按照随机数表法分为参比组和研究组,每组36例。参比组实行常规治疗,研究组采用常规治疗+采用鼻内镜鼻窦手术治疗,对比两组有效率、炎症因子指标和并发症发生率。结果研究组治疗总有效率(94.44%)显著高于参比组(72.22%),差异有统计学意义(χ^(2)=6.400,P=0.011)。治疗后,研究组的左、右鼻腔阻力小于参比组,差异有统计学意义(P均<0.05)。研究组治疗后的白细胞介素-5、肿瘤坏死因子-α水平低于参比组,差异有统计学意义(P均<0.05)。研究组并发症总发生率(术腔粘连闭塞、出血严重、鼻腔结痂)低于参比组,差异有统计学意义(P<0.05)。结论非侵袭性真菌性鼻-鼻窦炎扩大患者的治疗选用鼻内镜鼻窦手术治疗方式效果更好,有利于降低机体炎症水平,整体疗效高。

Objective To analyze the value of endoscopic sinus surgery in patients with noninvasive fungal rhinosinus⁃itis.Methods A total of 72 patients with non-invasive fungal rhinosinusitis-itis admitted to Linyi Hedong Hospital from June 2022 to June 2023 were selected as the research objects.According to the random number table method,they were divided into reference group and study group,with 36 cases in each group.The reference group was treated with routine treatment,and the study group was treated with routine treatment+nasal endoscopic sinus surgery.The effective rate,inflammatory factor indexes and complication rate were compared between the two groups.Results The total effective rate of treatment in the study group(94.44%)was significantly higher than that in the control group(72.22%),and the difference was statistically significant(χ^(2)=6.400,P=0.011).After treatment,the resistance in the left and right nasal cavities of the study group were lower than those of the control group,and the differences were sta⁃tistically significant(both P<0.05).The levels of interleukin-5 and tumor necrosis factor-αafter treatment of research group were lower than those of the control group,the differencs were statistically significant(both P<0.05).The total incidence of complications(surgical adhesion occlusion,severe bleeding,and nasal scab)in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion In the treatment of patients with noninvasive fungal rhinosinusitis,nasal endoscopic sinus surgery has a better effect,which is conducive to reducing the level of body inflammation,and the overall effect is high.