从非酒精性脂肪性肝病到代谢相关脂肪性肝疾病

From non-alcoholic fatty liver disease to metabolic associated fatty liver disease

非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)的患病率逐年上升,世界对该疾病的认识也逐渐深入。多年来,在对该领域不断的探索中发现术语NAFLD的局限性,因此国际多名专家经过多年讨论,最终联手提出了新术语“代谢相关脂肪性肝疾病(metabolic associated fatty liver disease,MAFLD)”,然而这一术语在过去几年饱受争议。从NAFLD到MAFLD,给科研及临床工作带来的影响是不容置疑的。因此,该文简要总结了现有的研究结论,通过多方面对比NAFLD和MAFLD,加深临床医师对MAFLD的认识。

The prevalence of non-alcoholic fatty liver disease(NAFLD)is increasing year by year,and the world's understanding of the disease has gradually deepened.Over the years,the limitation of the term NAFLD has been found during the continuous exploration of the disease,so a number of international experts have finally joined forces to propose the new term"metabolism associated fatty liver disease(MAFLD)"after many years of discussion,however this term has been controversial over the past few years.The impact from NAFLD to MAFLD on scientific research and clinical work is beyond question.Therefore,this paper briefly summarized the existing re⁃search conclusions,and made a variety of comparisons between NAFLD and MAFLD to deepen clinicians'understanding of MAFLD.