病毒宏基因组学在蜱媒病毒研究中的应用进展

Application progress of virus metagenomics in study of tick-borne virus

蜱是广泛分布于全球的专性吸血体外寄生虫,是世界上最主要的病媒生物之一,携带的病原体涵盖了细菌、病毒、螺旋体等。其中以蜱媒病毒为主要的虫媒病毒之一,给人类和动物的健康带来了极大的威胁。病毒宏基因组学是近年来基于宏基因组学兴起的病毒研究技术,它的出现为研究已知和未知病毒及其多样性提供了有力支持,给病毒研究带来了全新的技术手段和思路。本文综述了病毒宏基因组学在蜱媒病毒研究中的进展,以期为蜱媒病毒研究提供参考依据。

Ticks are specific blood-sucking ectoparasites which are widely distributed all over the world.They are one of the most important vector organism in the world,carrying pathogens including bacteria,viruses,spirochetes etc.Among them,tick-borne virus is the major arbovirus,which brings great burden to human and animal health.Virus metagenomics have been a virus research technology based on metagenomics in recent years.Its emergence provides strong support for the study of known and unknown viruses and their diversity,and brings new technical means and ideas to virus research.This paper reviews the research progress of viral metagenomics in tick-borne virus research to provide useful reference for tick-borne virus research.