全静脉营养在危重新生儿治疗中的临床应用价值研究

Clinical Application Value of Total Intravenous Nutrition in the Treatment of Critically Ill Newborns

目的分析危重新生儿治疗中行全静脉营养支持的效果。方法方便选取2021年1月—2023年6月邳州市人民医院收治的78例危重新生儿为研究对象,采用随机数表法分为对照组和观察组,每组39例。对照组采用一般支持治疗,观察组采用全静脉营养支持治疗。对比两组治疗时间、并发症发生率及体质量变化情况。结果观察组静脉营养时间(8.45±1.39)d、达全胃肠道喂养时间(9.26±1.87)d、恢复出生体质量时间(4.89±0.89)d、住院时间为(11.46±2.07)d,均短于对照组的(10.56±2.12)、(12.44±2.53)、(7.11±1.56)、(15.45±2.23)d,差异有统计学意义(t=5.198、6.312、7.719、8.189,P均<0.05)。观察组并发症发生率为5.13%,较对照组的20.51%低,差异有统计学意义(χ^(2)=4.129,P<0.05)。观察组持续体质量下降时间(3.41±0.79)d短于对照组的(5.15±1.16)d,每日体质量增加值为(12.13±3.42)g高于对照组的(7.89±1.45)g,差异有统计学意义(t=7.743、7.128,P均<0.05)。结论全静脉营养支持在危重新生儿治疗中可缩短患儿静脉营养、达全胃肠道喂养、恢复出生体质量及住院时间,能够避免患儿体质量持续下降,促进其体质量增长,且并发症少。

Objective To analyze the effect of total intravenous nutrition support in the treatment of critically ill newborns.Methods A total of 78 critically ill newborns admitted to Pizhou People's Hospital from January 2021 to June 2023 were conveniently selected as the study subjects.They were divided into control group and observation group by random number table method,with 39 cases in each group.The control group received general supportive treatment,and the observation group received total intravenous nutrition support treatment.The treatment time,the incidence of complications and changes of body mass were compared between the two groups.Results In the observation group,the time of intravenous nutrition was(8.45±1.39)d,the time of total gastrointestinal feeding was(9.26±1.87)d,the time of recovery of birth weight was(4.89±0.89)d,and the time of hospitalization was(11.46±2.07)d,were shorter than those of the control group(10.56±2.12)d,(12.44±2.53)d,(7.11±1.56)d,(15.45±2.23)d,and the differences were statistically significant(t=5.198,6.312,7.719,8.189,all P<0.05).The incidence of complications in the observation group was 5.13%,which was lower than 20.51%in the control group,and the difference was statistically significant(χ^(2)=4.129,P<0.05).The duration of body mass decline(3.41±0.79)d in the observation group was shorter than that in the control group(5.15±1.16)d,and the daily body mass gain(12.13±3.42)g was higher than that in the control group(7.89±1.45)g,and the differences were statistically significant(t=7.743,7.128,both P<0.05).Conclusion In the treatment of critically ill newborns,total intravenous nutrition support can shorten the intravenous nutrition of children,achieve whole gastrointestinal feeding,restore birth weight and hospital stay,avoid the continuous decline of body weight of children,promote the growth of body weight,and reduce complications.