100例急性呼吸道感染儿童五项病毒联合检测结果分析

Analysis of Five Virus Co-detection Results in 100 Children with Acute Respiratory Infection

目的探讨100例急性呼吸道感染(ARI)儿童五项病毒联合检测结果。方法选取2022年1月至2022年12月我院收治的ARI患儿共计100例,所有患儿均接受肺炎支原体(MP)、肺炎衣原体(CP)、呼吸道合胞病毒(RSV)、腺病毒(ADV)、柯萨奇B组病毒(CVB)的免疫球蛋白M(IgM)抗体检测,分析五项病毒阳性检出率,并比较不同性别、不同年龄段、不同病情程度、不同发病季节患儿的阳性率。结果100例患儿中共38例患儿检出病毒抗体阳性(38.00%),其中单种病毒感染36例(36.00%),混合病毒感染2例(2.00%),所有感染类型中以MP感染居多(15.00%);不同性别患儿的五项病毒阳性率比较差异无统计学意义(P>0.05);1~6岁患儿与<1岁、>6岁患儿相比MP阳性率、总阳性率更高(P<0.05),<1岁患儿与>6岁患儿相比总阳性率更高(P<0.05),<1岁患儿与1~6岁、>6岁患儿相比RSV阳性率更高(P<0.05);重度患儿与轻度、中度患儿相比RSV阳性率、总阳性率更高(P<0.05);冬季发病患儿与春季发病患儿相比总阳性率更高(P<0.05)。结论MP是引发儿童ARI的主要病毒,五项病毒分布受到年龄、病情程度及发病季节影响,1~6岁患儿易受到MP感染,<1岁患儿易受到RSV感染,患儿病情加重多由RSV导致,且病毒性ARI在冬季高发。

Objective To investigate the results of five virus tests in 100 children with acute respiratory infection(ARI).Methods A total of 100 children with ARI admitted to our hospital from January 2022 to December 2022 were selected.All the children were tested with immunoglobulin M(IgM)antibodies against mycoplasma pneumoniae(MP),Chlamydia pneumoniae(CP),respiratory syncytial virus(RSV),adenovirus(ADV)and Coxsackie Group B virus(CVB).The positive rate of five viruses was analyzed,and the positive rate of children with different sex,different age,different disease degree and different season was compared.Results A total of 38(38.00%)of the 100 children were positive for virus antibodies,including 36(36.00%)with single virus infection and 2(2.00%)with mixed virus infection.MP infection was the most common infection type(15.00%).There was no significant difference in the positive rates of five viruses among children of different genders(P>0.05).The positive rate of MP and total positive rate in children aged 1 to 6 years was higher than that in children aged 1 and>6 years(P<0.05),the positive rate of RSV in children aged 1 to 6 years was higher than that in children aged 1 to 6 years(P<0.05),and the positive rate of RSV in children aged 1 to 6 years was higher than that in children aged 1 to 6 years(P<0.05).The positive rate and total positive rate of RSV in severe children were higher than those in mild and moderate children(P<0.05).The total positive rate of children with winter disease was higher than that of children with spring disease(P<0.05).Conclusion MP is the main virus that causes ARI in children,and the distribution of the five viruses is affected by age,severity of disease and season of onset.Children aged 1 to 6 years are susceptible to MP infection,children younger than 1 year are susceptible to RSV infection,and the aggravation of disease in children is mostly caused by RSV,and viral ARI occurs more frequently in winter.