摘要
microRNA(miRNA)is a type of small non-coding RNA that can participate in cell proliferation and apoptosis by regulating gene expression.More and more evidences indicate that miRNA-200a is involved in the occurrence and development of non-alcoholic fatty liver disease,alcoholic liver disease,drug-induced liver injury,liver fibrosis,and hepatocellular carcinoma.Downstream target genes of serotonin,regulating related signal pathways and playing different roles in the progression of a variety of liver diseases,provide a reference for exploring the mechanism of a variety of chronic liver diseases.
基金
National Natural Science Foundation of China(No.81860790)
Guangxi Science and Technology Project(No.Guike AB20297002)
Guangxi Natural Science Foundation(No.2020GXNSFAA297160)
Guangxi Natural Science Foundation(No.2018GXNSFBA050050)
Guangxi First-class Discipline Integrated Traditional Chinese and Western Medicine Cultivation Discipline(No.2019XK159)
Guangxi Special Expert Special Project Funding(No.Gui Ren Cai Tong Zi(2019)13)。
